SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 7 VAL A 117
ILE A 191
ALA A 194
GLY A 119
THR A 121
 None
 1.45A 2xrzB-1vhvA:
1.9		 2xrzB-1vhvA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 123
CYH A 203
TYR A 187
PHE A 233
LEU A 228
 None
 1.26A 3bgrA-1vhvA:
0.0
3bgrB-1vhvA:
0.0		 3bgrA-1vhvA:
17.83
3bgrB-1vhvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		6 / 12 GLY A   6
GLY A  83
SER A 112
VAL A  87
ILE A  15
ASP A  14
 None
 1.49A 3cjtO-1vhvA:
2.3		 3cjtO-1vhvA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		3 / 3 GLU A  32
HIS A  91
THR A  35
 None
 0.78A 3hkuA-1vhvA:
undetectable		 3hkuA-1vhvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 8 TYR A  34
HIS A  91
ILE A  94
ALA A  88
 None
 0.97A 4eyzA-1vhvA:
undetectable		 4eyzA-1vhvA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 8 TYR A  34
HIS A  91
ILE A  94
ALA A  88
 None
 0.97A 4eyzB-1vhvA:
undetectable		 4eyzB-1vhvA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1vhv DIPHTHINE SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY A  83
VAL A  87
SER A 112
PHE A 159
ALA A 194
 None
 0.84A 5n0oA-1vhvA:
5.4		 5n0oA-1vhvA:
23.47