SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 5 LEU A 173
VAL A 176
LEU A 180
GLN A 183
 None
 0.86A 1fbmE-1vhzA:
undetectable		 1fbmE-1vhzA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 7 MET A 115
PHE A 164
MET A  51
ALA A  49
 None
 1.22A 1linA-1vhzA:
undetectable		 1linA-1vhzA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 5 SER A  78
LEU A 137
GLY A 101
GLU A  99
 None
 1.15A 3aiaA-1vhzA:
undetectable
3aiaB-1vhzA:
undetectable		 3aiaA-1vhzA:
19.47
3aiaB-1vhzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 5 ILE A  52
ARG A 168
GLU A  65
GLU A 166
 None
 1.46A 3ny4A-1vhzA:
undetectable		 3ny4A-1vhzA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 8 ILE A  55
LEU A  60
ILE A  52
PHE A  77
 None
 0.89A 4hb6A-1vhzA:
undetectable		 4hb6A-1vhzA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		5 / 11 LEU A 173
ARG A 177
ASP A 157
LEU A 159
LEU A  60
 None
 1.25A 4or0A-1vhzA:
undetectable		 4or0A-1vhzA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_E_SPME202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 5 GLU A 141
GLU A 143
TYR A  66
GLU A  65
 None
 1.49A 4r87E-1vhzA:
0.1		 4r87E-1vhzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 7 GLU A  99
SER A  78
ILE A  52
VAL A  50
 None
 1.21A 4tvtA-1vhzA:
undetectable		 4tvtA-1vhzA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		3 / 3 VAL A 127
TYR A  89
ALA A  92
 None
 0.56A 4ybnA-1vhzA:
0.0		 4ybnA-1vhzA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1vhz ADP COMPOUNDS
HYDROLASE NUDE
(Escherichia
coli) 		4 / 7 LEU A 158
VAL A  53
LEU A  60
LEU A 152
 None
 0.74A 6g9bA-1vhzA:
undetectable
6g9bB-1vhzA:
0.0		 6g9bA-1vhzA:
16.32
6g9bB-1vhzA:
20.28