SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vi6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vi6 30S RIBOSOMAL
PROTEIN S2P
(Archaeoglobus
fulgidus) 		6 / 12 ILE A  55
ALA A  59
ALA A  58
LEU A 155
VAL A  20
LEU A 143
 None
 1.49A 1fm9A-1vi6A:
undetectable		 1fm9A-1vi6A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1vi6 30S RIBOSOMAL
PROTEIN S2P
(Archaeoglobus
fulgidus) 		4 / 6 ALA A  59
GLU A 177
LEU A   9
LEU A  51
 None
 1.00A 1mt1D-1vi6A:
undetectable
1mt1E-1vi6A:
undetectable		 1mt1D-1vi6A:
19.31
1mt1E-1vi6A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 1vi6 30S RIBOSOMAL
PROTEIN S2P
(Archaeoglobus
fulgidus) 		4 / 6 LEU A  51
LEU A  46
ILE A  55
ARG A  54
 None
 0.99A 2rlfA-1vi6A:
undetectable
2rlfB-1vi6A:
undetectable		 2rlfA-1vi6A:
11.54
2rlfB-1vi6A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 1vi6 30S RIBOSOMAL
PROTEIN S2P
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  62
LEU A 174
LEU A 173
LEU A  51
LEU A 155
 None
 1.24A 3d90B-1vi6A:
undetectable		 3d90B-1vi6A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1vi6 30S RIBOSOMAL
PROTEIN S2P
(Archaeoglobus
fulgidus) 		5 / 8 VAL A 140
ILE A 138
VAL A  73
PHE A 119
VAL A 120
 NA  A 208 (-4.3A)
None
None
None
None
 1.36A 5l94A-1vi6A:
undetectable		 5l94A-1vi6A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1vi6 30S RIBOSOMAL
PROTEIN S2P
(Archaeoglobus
fulgidus) 		5 / 10 GLY A  19
ALA A 168
LEU A 167
GLY A 163
LEU A 104
 None
 1.31A 6hqbA-1vi6A:
undetectable
6hqbJ-1vi6A:
undetectable		 6hqbA-1vi6A:
15.38
6hqbJ-1vi6A:
12.98