SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		4 / 6 LEU A 192
LEU A 180
GLY A 163
ILE A 165
 None
 0.89A 1mt1G-1vi7A:
undetectable
1mt1J-1vi7A:
undetectable		 1mt1G-1vi7A:
13.57
1mt1J-1vi7A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		4 / 7 ILE A 165
LEU A 192
LEU A 180
GLY A 163
 None
 0.90A 1mt1H-1vi7A:
undetectable
1mt1K-1vi7A:
undetectable		 1mt1H-1vi7A:
17.89
1mt1K-1vi7A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		4 / 8 LEU A 192
LEU A 180
GLY A 163
ILE A 165
 None
 0.88A 1n13A-1vi7A:
undetectable
1n13F-1vi7A:
undetectable		 1n13A-1vi7A:
13.57
1n13F-1vi7A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		3 / 3 THR A 133
ASP A  65
SER A  67
 None
 0.69A 2nxeA-1vi7A:
3.1		 2nxeA-1vi7A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		3 / 3 THR A 133
ASP A  65
SER A  67
 None
 0.67A 2nxeB-1vi7A:
3.4		 2nxeB-1vi7A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 12 LEU A 116
LEU A 111
PHE A  25
GLU A  77
HIS A  54
 None
 0.98A 4aqlA-1vi7A:
undetectable		 4aqlA-1vi7A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 12 GLU A 141
PRO A 138
GLU A  97
HIS A  31
GLY A  34
 None
 1.40A 4hvcA-1vi7A:
undetectable		 4hvcA-1vi7A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 12 GLU A 141
PRO A 138
GLU A  97
HIS A  31
GLY A  34
 None
 1.46A 4olfA-1vi7A:
undetectable		 4olfA-1vi7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		3 / 3 PRO A  85
MET A  86
TYR A 120
 None
 1.09A 4qa0B-1vi7A:
undetectable		 4qa0B-1vi7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		3 / 3 PRO A  85
MET A  86
TYR A 120
 None
 1.06A 4qa0A-1vi7A:
undetectable		 4qa0A-1vi7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		3 / 3 PRO A  85
MET A  86
TYR A 120
 None
 1.00A 4qa2B-1vi7A:
undetectable		 4qa2B-1vi7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.88A 4qvlK-1vi7A:
undetectable
4qvlL-1vi7A:
undetectable		 4qvlK-1vi7A:
24.90
4qvlL-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.88A 4qvlY-1vi7A:
undetectable
4qvlZ-1vi7A:
undetectable		 4qvlY-1vi7A:
24.90
4qvlZ-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 10 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.87A 4qvmY-1vi7A:
undetectable
4qvmZ-1vi7A:
undetectable		 4qvmY-1vi7A:
23.85
4qvmZ-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.87A 4qvwK-1vi7A:
undetectable
4qvwL-1vi7A:
undetectable		 4qvwK-1vi7A:
24.90
4qvwL-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.88A 4qvwY-1vi7A:
undetectable
4qvwZ-1vi7A:
undetectable		 4qvwY-1vi7A:
24.90
4qvwZ-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.89A 4qw1K-1vi7A:
undetectable
4qw1L-1vi7A:
undetectable		 4qw1K-1vi7A:
24.48
4qw1L-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.89A 5bxnK-1vi7A:
undetectable
5bxnL-1vi7A:
undetectable		 5bxnK-1vi7A:
24.90
5bxnL-1vi7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1vi7 HYPOTHETICAL PROTEIN
YIGZ
(Escherichia
coli) 		5 / 11 THR A  99
ALA A 100
GLY A  62
GLY A  96
SER A  93
 None
 0.88A 5bxnY-1vi7A:
undetectable
5bxnZ-1vi7A:
undetectable		 5bxnY-1vi7A:
24.90
5bxnZ-1vi7A:
19.51