SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1via'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		4 / 8 SER A  15
SER A  18
GLY A  82
GLY A  11
 None
None
SO4  A 176 (-3.4A)
None
 0.69A 1aq7A-1viaA:
undetectable		 1aq7A-1viaA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		4 / 8 ASP A  34
SER A  18
SER A  15
GLY A  81
 None
 0.78A 1f5lA-1viaA:
undetectable		 1f5lA-1viaA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		5 / 12 ALA A  79
GLY A  81
ALA A  21
ARG A  22
PHE A  32
 None
 1.13A 1ve3A-1viaA:
undetectable		 1ve3A-1viaA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		4 / 8 SER A  15
SER A  18
GLY A  82
GLY A  11
 None
None
SO4  A 176 (-3.4A)
None
 0.76A 2vinA-1viaA:
undetectable		 2vinA-1viaA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		5 / 10 PHE A  51
GLY A  82
GLY A  81
THR A  80
ILE A  10
 None
SO4  A 176 (-3.4A)
None
None
None
 1.26A 3fw1A-1viaA:
2.5		 3fw1A-1viaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		4 / 8 ASP A  34
SER A 116
LEU A 110
ASP A 111
 None
 1.00A 3m0wE-1viaA:
undetectable
3m0wF-1viaA:
undetectable
3m0wG-1viaA:
undetectable
3m0wH-1viaA:
undetectable		 3m0wE-1viaA:
22.76
3m0wF-1viaA:
22.76
3m0wG-1viaA:
22.76
3m0wH-1viaA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		5 / 11 PHE A  84
GLY A  81
SER A  35
PHE A  70
GLY A  94
 None
 1.02A 3v3nA-1viaA:
undetectable		 3v3nA-1viaA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		5 / 11 PHE A  84
GLY A  81
SER A  35
PHE A  70
GLY A  94
 None
 1.01A 3v3nD-1viaA:
1.4		 3v3nD-1viaA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		5 / 11 GLY A  83
ALA A  79
ASP A  34
SER A  35
PHE A  59
 SO4  A 176 (-4.2A)
None
None
None
None
 1.21A 4wnuC-1viaA:
0.0		 4wnuC-1viaA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1via SHIKIMATE KINASE
(Campylobacter
jejuni) 		3 / 3 ARG A 134
PHE A  51
ARG A  60
 SO4  A 176 (-3.0A)
None
SO4  A 176 (-2.8A)
 0.94A 5y9yA-1viaA:
0.0		 5y9yA-1viaA:
22.05