SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 TYR A 191
GLY A  75
THR A  76
TYR A 199
 None
 0.93A 2g70A-1vicA:
undetectable		 2g70A-1vicA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 TYR A 191
GLY A  75
THR A  76
TYR A 199
 None
 0.92A 2g70B-1vicA:
undetectable		 2g70B-1vicA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 7 ILE A  93
ILE A 108
LEU A 126
ILE A 188
 None
 0.88A 2q83A-1vicA:
undetectable		 2q83A-1vicA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ILE A 104
PRO A 105
ASN A 115
GLY A 187
 None
 0.93A 3em0B-1vicA:
undetectable		 3em0B-1vicA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 SER A  74
GLU A 214
ILE A   7
VAL A  33
 None
 0.99A 4dx7B-1vicA:
undetectable		 4dx7B-1vicA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 THR A  76
SER A  74
GLY A 187
GLY A  99
PRO A   8
 None
 1.36A 4uinH-1vicA:
undetectable
4uinL-1vicA:
undetectable		 4uinH-1vicA:
22.22
4uinL-1vicA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 LEU A 116
ALA A 117
ASN A  91
VAL A  95
ALA A 190
 None
 1.03A 4x20B-1vicA:
undetectable		 4x20B-1vicA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ILE A   7
ALA A  63
GLY A  62
ALA A  58
ILE A  47
 None
 0.84A 5kb6A-1vicA:
undetectable		 5kb6A-1vicA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 ILE A   7
ALA A  63
GLY A  62
ALA A  58
ILE A  47
 None
 0.86A 5kb6B-1vicA:
undetectable		 5kb6B-1vicA:
21.64