SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vio'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 8 ILE A 121
TRP A 117
VAL A 231
CYH A 128
 None
 1.22A 2xz5A-1vioA:
undetectable
2xz5C-1vioA:
undetectable		 2xz5A-1vioA:
19.68
2xz5C-1vioA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 8 ILE A 121
TRP A 117
VAL A 231
CYH A 128
 None
 1.22A 2xz5C-1vioA:
undetectable
2xz5D-1vioA:
undetectable		 2xz5C-1vioA:
19.68
2xz5D-1vioA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 7 TYR A  62
GLU A  59
LEU A 222
TRP A 117
 None
BU1  A 242 (-3.6A)
None
None
 1.38A 3k8mA-1vioA:
undetectable		 3k8mA-1vioA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 7 TYR A  62
GLU A  59
LEU A 222
TRP A 117
 None
BU1  A 242 (-3.6A)
None
None
 1.36A 3k8mB-1vioA:
undetectable		 3k8mB-1vioA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		5 / 10 LEU A  54
ILE A  29
VAL A  39
GLY A  37
ILE A  47
 None
 1.00A 3s43B-1vioA:
undetectable		 3s43B-1vioA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 8 TRP A 117
VAL A 231
CYH A 128
ILE A 121
 None
 1.29A 4bqtC-1vioA:
undetectable
4bqtD-1vioA:
undetectable		 4bqtC-1vioA:
19.68
4bqtD-1vioA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		5 / 12 LEU A 166
THR A 161
ILE A 178
GLN A 185
ILE A 152
 None
 1.03A 4rp8C-1vioA:
undetectable		 4rp8C-1vioA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 6 ASP A 114
ALA A  98
THR A 112
TYR A  62
 None
 1.48A 4w5rA-1vioA:
undetectable		 4w5rA-1vioA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		4 / 6 ASP A 114
ALA A  98
THR A 112
TYR A  62
 None
 1.41A 4w5tA-1vioA:
undetectable		 4w5tA-1vioA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1vio RIBOSOMAL SMALL
SUBUNIT
PSEUDOURIDINE
SYNTHASE A
(Haemophilus
influenzae) 		3 / 3 VAL A 140
GLU A 141
ILE A 168
 None
 0.62A 6f7lB-1vioA:
undetectable		 6f7lB-1vioA:
19.24