SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
LYS A  69
 None
 1.17A 1th6A-1vipA:
21.6		 1th6A-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
 1.01A 1th6A-1vipA:
21.6		 1th6A-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
LYS A  69
 None
 1.16A 2armA-1vipA:
21.6		 2armA-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
 0.99A 2armA-1vipA:
21.6		 2armA-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
 0.58A 2dpzA-1vipA:
22.2		 2dpzA-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 9 LYS A  16
TYR A 113
LYS A 115
TYR A 117
PRO A 121
 None
 0.79A 3bjwG-1vipA:
21.1		 3bjwG-1vipA:
49.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 9 LYS A  16
TYR A 113
LYS A 115
TYR A 117
PRO A 121
 None
 0.79A 3bjwA-1vipA:
21.0		 3bjwA-1vipA:
49.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		4 / 8 LYS A  16
TYR A 113
LYS A 115
PRO A 121
 None
 0.86A 3bjwD-1vipA:
20.8		 3bjwD-1vipA:
49.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.45A 3fo7A-1vipA:
21.5		 3fo7A-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.49A 3h1xA-1vipA:
21.7		 3h1xA-1vipA:
57.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		4 / 5 GLY A  35
LYS A  36
GLU A 130
GLY A 128
 None
None
None
SO4  A 300 (-3.3A)
 0.85A 3onnA-1vipA:
undetectable		 3onnA-1vipA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
 0.50A 3oshA-1vipA:
18.8		 3oshA-1vipA:
43.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 9 VAL A  47
ALA A 102
PHE A 106
TYR A 113
TYR A  25
 None
 1.44A 4lb2B-1vipA:
2.0		 4lb2B-1vipA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 1vip PHOSPHOLIPASE A2
(Daboia
russelii) 		5 / 12 ARG A 100
PHE A   5
ALA A 103
ALA A 102
VAL A 101
 None
 1.07A 6c2mC-1vipA:
undetectable		 6c2mC-1vipA:
18.49