SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1viw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		4 / 6 VAL B 161
VAL B 165
ILE B 137
ARG B 108
 None
 1.14A 1iepA-1viwB:
undetectable		 1iepA-1viwB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		3 / 3 LYS B 203
ILE B  51
THR B  56
 None
 0.68A 1rx3A-1viwB:
undetectable		 1rx3A-1viwB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		4 / 6 PHE B  66
VAL B 135
LEU B 150
SER B  78
 None
 1.07A 1wrlB-1viwB:
undetectable		 1wrlB-1viwB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		5 / 12 ASP B  83
LEU B  82
ILE B 137
SER B 199
PHE B  66
 None
None
None
NAG  B 509 (-2.4A)
None
 1.42A 1xmuA-1viwB:
undetectable		 1xmuA-1viwB:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		5 / 12 ASP B  83
LEU B  82
ILE B 137
SER B 199
PHE B  66
 None
None
None
NAG  B 509 (-2.4A)
None
 1.46A 1xoqA-1viwB:
undetectable		 1xoqA-1viwB:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		5 / 12 ASP B  83
LEU B  82
ILE B 137
SER B 199
PHE B  66
 None
None
None
NAG  B 509 (-2.4A)
None
 1.46A 1xoqB-1viwB:
undetectable		 1xoqB-1viwB:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		4 / 7 PHE B  62
VAL B  98
THR B  99
VAL B 148
 None
 0.93A 2qblA-1viwB:
undetectable		 2qblA-1viwB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		4 / 8 PHE B  62
VAL B  98
THR B  99
VAL B 148
 None
 0.83A 2qbmA-1viwB:
undetectable		 2qbmA-1viwB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		3 / 3 PHE B 105
TYR B 186
LEU B  82
 None
 0.61A 3keeB-1viwB:
undetectable		 3keeB-1viwB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		3 / 3 PHE B 105
TYR B 186
LEU B  82
 None
 0.68A 3sueB-1viwB:
undetectable		 3sueB-1viwB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		3 / 3 LYS B 203
ILE B  51
THR B  56
 None
 0.70A 4gh8A-1viwB:
undetectable		 4gh8A-1viwB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		4 / 8 ASN B  15
VAL B  24
LEU B  30
GLY B 178
 None
 0.86A 4r3aA-1viwB:
undetectable		 4r3aA-1viwB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1viw ALPHA-AMYLASE-INHIBI
TOR
(Phaseolus
vulgaris) 		4 / 7 ASP B 103
GLY B 184
THR B  72
GLU B 191
 None
 1.12A 5btfA-1viwB:
undetectable
5btfC-1viwB:
undetectable
5btfD-1viwB:
undetectable		 5btfA-1viwB:
15.64
5btfC-1viwB:
15.64
5btfD-1viwB:
20.45