SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 PHE A 205
LEU A  79
LEU A 121
 None
 0.67A 1mx1E-1vjgA:
3.0		 1mx1E-1vjgA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 TRP A 204
PHE A 205
TRP A 201
 None
 1.46A 1r15C-1vjgA:
3.1		 1r15C-1vjgA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 TRP A 204
PHE A 205
TRP A 201
 None
 1.46A 1r15F-1vjgA:
3.2		 1r15F-1vjgA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 TRP A 204
PHE A 205
TRP A 201
 None
 1.46A 1r15G-1vjgA:
3.1		 1r15G-1vjgA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 TRP A 204
PHE A 205
TRP A 201
 None
 1.45A 1r15H-1vjgA:
undetectable		 1r15H-1vjgA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 ILE A 100
ILE A 104
THR A  89
 None
 0.60A 1rg7A-1vjgA:
undetectable		 1rg7A-1vjgA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		4 / 6 PHE A 191
GLY A  15
GLY A  51
ASN A  49
 None
 0.92A 2qr2A-1vjgA:
4.6
2qr2B-1vjgA:
4.3		 2qr2A-1vjgA:
20.08
2qr2B-1vjgA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		4 / 7 TYR A  47
PHE A  13
ASN A  20
GLY A  51
 None
 0.97A 3kmoB-1vjgA:
undetectable		 3kmoB-1vjgA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 TYR A  47
LEU A 117
ARG A  71
 None
 0.69A 3sufB-1vjgA:
undetectable		 3sufB-1vjgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		4 / 7 PRO A 127
ARG A 137
GLY A 135
PRO A 134
 None
 1.31A 3ucbB-1vjgA:
undetectable		 3ucbB-1vjgA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		3 / 3 PRO A 183
TYR A 188
GLY A 186
 None
 0.74A 4g2zA-1vjgA:
undetectable		 4g2zA-1vjgA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		4 / 7 SER A  83
GLY A  23
ASP A  24
GLU A 174
 None
 0.87A 4koeA-1vjgA:
undetectable
4koeB-1vjgA:
undetectable
4koeD-1vjgA:
3.4		 4koeA-1vjgA:
17.85
4koeB-1vjgA:
17.85
4koeD-1vjgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 12 CYH A  27
PRO A  25
ARG A  33
TYR A 188
GLY A  29
 None
 1.40A 4kosA-1vjgA:
0.8		 4kosA-1vjgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 12 CYH A  27
PRO A  25
ARG A  33
TYR A 188
GLY A  29
 None
 1.41A 4kotA-1vjgA:
0.6		 4kotA-1vjgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 11 CYH A  27
PRO A  25
ARG A  33
TYR A 188
GLY A  29
 None
 1.41A 4koxA-1vjgA:
0.6		 4koxA-1vjgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOY_A_CSCA214_1
(UNCHARACTERIZED
PROTEIN)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 11 CYH A  27
PRO A  25
ARG A  33
TYR A 188
GLY A  29
 None
 1.39A 4koyA-1vjgA:
undetectable		 4koyA-1vjgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		4 / 5 PRO A  96
GLY A  94
ASP A  16
ASP A 133
 None
 0.90A 4n48B-1vjgA:
undetectable		 4n48B-1vjgA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 11 ILE A 123
SER A  57
ILE A  60
ARG A  63
TYR A 158
 None
 1.18A 4qi9C-1vjgA:
undetectable		 4qi9C-1vjgA:
25.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE A 123
SER A  57
ILE A  60
ARG A  63
TYR A 158
 None
 1.09A 5hi6A-1vjgA:
undetectable		 5hi6A-1vjgA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 1vjg PUTATIVE LIPASE FROM
THE G-D-S-L FAMILY
(Nostoc
sp.
PCC
7120) 		5 / 12 ASP A 179
ASP A  16
ASN A  87
ARG A 136
GLU A 130
 None
 1.47A 6gnfC-1vjgA:
3.1		 6gnfC-1vjgA:
18.58