SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vjk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		4 / 7 PHE A  45
ALA A  16
ILE A  23
GLU A  21
 None
 1.01A 1oniA-1vjkA:
undetectable
1oniB-1vjkA:
undetectable		 1oniA-1vjkA:
21.09
1oniB-1vjkA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		4 / 7 PHE A  45
ALA A  16
ILE A  23
GLU A  21
 None
 0.98A 1oniD-1vjkA:
undetectable
1oniF-1vjkA:
undetectable		 1oniD-1vjkA:
21.09
1oniF-1vjkA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		4 / 7 ILE A  23
GLU A  21
PHE A  45
ALA A  16
 None
 1.10A 1oniG-1vjkA:
undetectable
1oniI-1vjkA:
undetectable		 1oniG-1vjkA:
21.09
1oniI-1vjkA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		3 / 3 GLU A  37
LEU A  34
ASP A  33
 None
 0.47A 3ko0A-1vjkA:
undetectable		 3ko0A-1vjkA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		3 / 3 GLU A  37
LEU A  34
ASP A  33
 None
 0.43A 3ko0T-1vjkA:
undetectable		 3ko0T-1vjkA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		3 / 3 GLU A  21
ARG A  41
HIS A  42
 None
 0.78A 4kf9A-1vjkA:
undetectable		 4kf9A-1vjkA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 1vjk MOLYBDOPTERIN
CONVERTING FACTOR,
SUBUNIT 1
(Pyrococcus
furiosus) 		5 / 12 GLU A  48
GLN A  14
ILE A  38
VAL A  83
VAL A   6
 None
 1.13A 5dpdA-1vjkA:
undetectable		 5dpdA-1vjkA:
11.20