SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		5 / 12 ILE A  20
GLY A 101
VAL A  74
GLY A  17
HIS A   0
 None
 1.14A 1kiaB-1vjnA:
undetectable		 1kiaB-1vjnA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		5 / 12 ILE A  20
GLY A 101
VAL A  74
GLY A  17
HIS A   0
 None
 1.14A 1kiaC-1vjnA:
undetectable		 1kiaC-1vjnA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		5 / 10 GLY A 135
LEU A 167
TYR A 162
THR A 137
GLY A 136
 None
 1.37A 1kvlA-1vjnA:
undetectable		 1kvlA-1vjnA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		5 / 12 LEU A 130
ILE A 157
VAL A 121
ASP A 150
PHE A 177
 None
 1.38A 2qo4A-1vjnA:
undetectable		 2qo4A-1vjnA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		3 / 3 CYH A 107
HIS A 108
PHE A  99
 None
 0.82A 3cr4X-1vjnA:
undetectable		 3cr4X-1vjnA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		6 / 12 LEU A  13
VAL A  40
ILE A  63
GLY A  78
VAL A  96
ILE A  20
 None
 1.37A 3nu5A-1vjnA:
undetectable		 3nu5A-1vjnA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		6 / 10 LEU A  13
VAL A  40
ILE A  63
GLY A  78
VAL A  96
ILE A  20
 None
 1.46A 3oxwB-1vjnA:
undetectable		 3oxwB-1vjnA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		4 / 8 ALA A 145
VAL A 148
LEU A 152
LEU A 131
 None
 0.50A 3roxA-1vjnA:
undetectable		 3roxA-1vjnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		3 / 3 ASP A 128
GLU A 100
GLY A 103
 None
 0.67A 3w9tA-1vjnA:
undetectable		 3w9tA-1vjnA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		5 / 12 PRO A 173
PRO A 142
ILE A 157
VAL A 132
ILE A 140
 None
 1.45A 4eb6B-1vjnA:
undetectable
4eb6C-1vjnA:
undetectable		 4eb6B-1vjnA:
19.31
4eb6C-1vjnA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 1vjn ZN-DEPENDENT
HYDROLASE OF
METALLO-BETA-LACTAMA
SE SUPERFAMILY
TM0207
(Thermotoga
maritima) 		5 / 12 ILE A  20
ALA A  12
PHE A  99
VAL A  74
GLY A  73
 None
 0.79A 5j2tC-1vjnA:
undetectable		 5j2tC-1vjnA:
18.08