SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vjo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 8 ILE A 150
LEU A 181
ALA A 116
VAL A 100
 None
 0.63A 1a29A-1vjoA:
undetectable		 1a29A-1vjoA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		3 / 3 TRP A 285
VAL A 191
PRO A 192
 None
 0.99A 1rh0A-1vjoA:
undetectable		 1rh0A-1vjoA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 6 SER A 187
ILE A 193
THR A 221
ALA A  85
 None
 0.98A 1w0gA-1vjoA:
undetectable		 1w0gA-1vjoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 8 GLY A 216
GLY A  82
THR A  83
ALA A  84
 None
PLP  A 400 (-3.2A)
PLP  A 400 (-3.5A)
None
 0.48A 2ej3A-1vjoA:
undetectable		 2ej3A-1vjoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A 216
GLY A  82
THR A  83
ALA A  84
ALA A  85
 None
PLP  A 400 (-3.2A)
PLP  A 400 (-3.5A)
None
None
 0.72A 2ej3B-1vjoA:
undetectable		 2ej3B-1vjoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 8 GLY A 216
GLY A  82
THR A  83
ALA A  84
ALA A  85
 None
PLP  A 400 (-3.2A)
PLP  A 400 (-3.5A)
None
None
 0.75A 2ej3C-1vjoA:
undetectable		 2ej3C-1vjoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 8 LEU A 273
ILE A  60
LEU A  64
LEU A 211
 None
 0.67A 2xfhA-1vjoA:
undetectable		 2xfhA-1vjoA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE A 322
ILE A 373
LEU A 372
LEU A  26
VAL A 343
 None
 0.92A 3adsB-1vjoA:
undetectable		 3adsB-1vjoA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 188
ALA A 156
ALA A 203
VAL A 200
LEU A 139
 None
 1.29A 3b0wA-1vjoA:
undetectable		 3b0wA-1vjoA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 6 PHE A 134
GLN A 164
LEU A 151
LEU A 153
 None
 1.11A 3bgdA-1vjoA:
undetectable		 3bgdA-1vjoA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 VAL A 154
LEU A 153
GLY A 103
SER A 127
PRO A 129
 None
 1.21A 3bjwE-1vjoA:
undetectable		 3bjwE-1vjoA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 7 ASN A 239
ALA A  91
ARG A 111
ALA A  84
 None
 1.11A 3twpB-1vjoA:
undetectable		 3twpB-1vjoA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 7 ASN A 239
ALA A  91
ARG A 111
ALA A  84
 None
 1.01A 3twpC-1vjoA:
2.1		 3twpC-1vjoA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 179
PHE A 220
ILE A 227
LEU A 230
VAL A 237
 None
 1.14A 3w68B-1vjoA:
undetectable		 3w68B-1vjoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.23A 4e47A-1vjoA:
undetectable		 4e47A-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.26A 4e47B-1vjoA:
undetectable		 4e47B-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.25A 4e47C-1vjoA:
undetectable		 4e47C-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.31A 4jdsA-1vjoA:
undetectable		 4jdsA-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.29A 4jdsB-1vjoA:
undetectable		 4jdsB-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.26A 4jdsC-1vjoA:
undetectable		 4jdsC-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.22A 4jlgA-1vjoA:
undetectable		 4jlgA-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A 162
GLY A 131
GLU A 132
GLY A 109
HIS A 155
 None
 1.28A 4jlgA-1vjoA:
undetectable		 4jlgA-1vjoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 5 ARG A 356
GLY A 344
GLY A  27
PRO A  28
 None
 0.94A 4u9uA-1vjoA:
undetectable		 4u9uA-1vjoA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 112
LEU A 202
ALA A  91
VAL A  94
ALA A  93
 None
 1.08A 4x1kD-1vjoA:
undetectable		 4x1kD-1vjoA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 9 PRO A  28
LEU A 314
GLY A 161
GLU A 157
THR A 186
 None
None
None
None
PLP  A 400 (-4.5A)
 1.04A 4x3mA-1vjoA:
undetectable		 4x3mA-1vjoA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 7 TYR A 107
ARG A 356
SER A 159
GLU A 157
 None
 1.12A 4xzkA-1vjoA:
undetectable		 4xzkA-1vjoA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 162
GLY A 131
GLU A 132
GLY A 103
HIS A 155
 None
 1.28A 5ayfA-1vjoA:
undetectable		 5ayfA-1vjoA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A  82
GLY A  80
VAL A 185
THR A 184
ALA A  88
 PLP  A 400 (-3.2A)
None
PLP  A 400 (-4.2A)
None
None
 1.07A 5kpcB-1vjoA:
undetectable		 5kpcB-1vjoA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		4 / 8 ASN A  92
LEU A 242
LEU A 247
ILE A  76
 None
 0.90A 6cb4A-1vjoA:
undetectable		 6cb4A-1vjoA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A 117
GLY A 120
ILE A  90
VAL A 123
ILE A 102
 None
 0.96A 6ectA-1vjoA:
undetectable		 6ectA-1vjoA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1vjo ALANINE--GLYOXYLATE
AMINOTRANSFERASE
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A 117
GLY A 120
ILE A  90
VAL A 123
ILE A 102
 None
 0.94A 6ecxA-1vjoA:
undetectable		 6ecxA-1vjoA:
21.36