SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 433
PHE A 309
PHE A 233
PHE A 214
 None
 1.19A 1e71M-1vjvA:
undetectable		 1e71M-1vjvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 433
PHE A 309
PHE A 233
PHE A 214
 None
 1.21A 1e72M-1vjvA:
undetectable		 1e72M-1vjvA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 7 PRO A 181
VAL A 182
THR A 117
LEU A 120
 None
 0.90A 1jgsA-1vjvA:
undetectable		 1jgsA-1vjvA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 188
HIS A 157
ILE A 156
 None
 0.68A 1s9pB-1vjvA:
0.0		 1s9pB-1vjvA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 229
PHE A 218
PHE A 214
 None
 0.79A 2od9A-1vjvA:
undetectable		 2od9A-1vjvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 229
PHE A 218
PHE A 214
 None
 0.79A 2qqgA-1vjvA:
undetectable		 2qqgA-1vjvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 6 THR A 311
LYS A 260
PHE A 233
PHE A 229
 None
 1.12A 3elzB-1vjvA:
0.0		 3elzB-1vjvA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 495
ARG A 129
ASP A 406
 None
 1.39A 3o7wA-1vjvA:
undetectable		 3o7wA-1vjvA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		5 / 11 ARG A 316
LEU A 490
ALA A 122
ILE A 452
ILE A 436
 None
 1.26A 3oxxB-1vjvA:
undetectable		 3oxxB-1vjvA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 7 GLN A 338
GLU A 359
ARG A 361
GLU A 364
 None
 1.19A 3ql6A-1vjvA:
0.0		 3ql6A-1vjvA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 338
ASP A 340
ARG A 361
GLU A 364
 None
 0.99A 3r4xA-1vjvA:
0.0		 3r4xA-1vjvA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 338
ASP A 340
ARG A 361
GLU A 364
 None
 1.11A 3r55A-1vjvA:
0.0		 3r55A-1vjvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 128
ARG A 129
ASP A 135
ASN A 131
 None
 1.36A 3wfaA-1vjvA:
0.0
3wfaB-1vjvA:
0.0		 3wfaA-1vjvA:
20.95
3wfaB-1vjvA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 162
GLU A 163
GLN A 159
ILE A 156
 None
 0.76A 4mj8A-1vjvA:
undetectable		 4mj8A-1vjvA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 277
LEU A 280
GLY A 279
THR A 269
ILE A 265
 None
 1.34A 4oktA-1vjvA:
undetectable		 4oktA-1vjvA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 6 GLN A 338
ASP A 340
ARG A 361
GLU A 364
 None
 1.13A 4qyqC-1vjvA:
0.0		 4qyqC-1vjvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 233
ILE A 160
PHE A 214
LEU A 127
LEU A 133
 None
 1.25A 4xumA-1vjvA:
0.0		 4xumA-1vjvA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 8 THR A 311
LEU A 261
PRO A 307
LEU A 276
 None
 0.90A 5g48A-1vjvA:
undetectable		 5g48A-1vjvA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 6 GLN A 338
ASP A 340
ARG A 361
GLU A 364
 None
 1.13A 5hpwC-1vjvA:
0.0		 5hpwC-1vjvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		5 / 8 GLY A 110
ASN A 121
GLN A 125
ALA A 450
PHE A 464
 None
 0.47A 5xu8A-1vjvA:
30.3		 5xu8A-1vjvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 438
ALA A 441
SER A 445
GLY A 446
 None
 1.09A 5yodB-1vjvA:
undetectable		 5yodB-1vjvA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 438
ALA A 441
SER A 445
GLY A 446
 None
 1.13A 5yodD-1vjvA:
undetectable		 5yodD-1vjvA:
18.77