SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		5 / 10 ALA A  88
LEU A  85
ILE A 175
HIS A 153
LEU A 156
 None
 1.45A 1a52A-1vjzA:
undetectable		 1a52A-1vjzA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		5 / 10 ALA A  88
LEU A  85
ILE A 175
HIS A 153
LEU A 156
 None
 1.45A 1a52B-1vjzA:
undetectable		 1a52B-1vjzA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.10A 1c8lA-1vjzA:
0.4		 1c8lA-1vjzA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 ILE A 127
ARG A 171
PHE A 134
PHE A  64
 None
 1.46A 1e73M-1vjzA:
19.9		 1e73M-1vjzA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 GLN A  35
ILE A  81
HIS A  80
 None
 0.62A 1fm9A-1vjzA:
undetectable		 1fm9A-1vjzA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.08A 1gfzA-1vjzA:
undetectable		 1gfzA-1vjzA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 GLN A  35
ILE A  81
HIS A  80
 None
 0.65A 1k74A-1vjzA:
undetectable		 1k74A-1vjzA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.11A 1l5qA-1vjzA:
undetectable		 1l5qA-1vjzA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.13A 1l5qB-1vjzA:
undetectable		 1l5qB-1vjzA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.09A 1l7xA-1vjzA:
undetectable		 1l7xA-1vjzA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.12A 1l7xB-1vjzA:
1.5		 1l7xB-1vjzA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 8 SER A 133
PHE A 256
ASN A 286
LEU A 172
 None
 1.02A 1lhvA-1vjzA:
undetectable		 1lhvA-1vjzA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		5 / 11 ASN A 138
GLU A 139
TYR A 200
GLU A 259
TRP A 292
 None
 0.89A 2v3dB-1vjzA:
16.5		 2v3dB-1vjzA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 TYR A 200
GLU A 139
ASN A  94
 None
 0.86A 2y7hC-1vjzA:
0.0		 2y7hC-1vjzA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		5 / 12 PHE A  30
ILE A  79
LEU A 136
ASP A 176
GLU A 139
 None
 1.28A 3aocC-1vjzA:
undetectable		 3aocC-1vjzA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.11A 3dd1A-1vjzA:
undetectable		 3dd1A-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.07A 3dd1B-1vjzA:
undetectable		 3dd1B-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.12A 3ddsA-1vjzA:
0.7		 3ddsA-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.10A 3ddsB-1vjzA:
undetectable		 3ddsB-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.10A 3ddwA-1vjzA:
undetectable		 3ddwA-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 6 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.09A 3ddwB-1vjzA:
undetectable		 3ddwB-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 5 ILE A  67
PHE A  63
ASP A  62
GLU A  61
 None
 0.98A 3kp6A-1vjzA:
undetectable
3kp6B-1vjzA:
0.0		 3kp6A-1vjzA:
19.39
3kp6B-1vjzA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_2
(ALPHA-GLUCOSIDASE)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 5 ILE A  79
TYR A 124
TRP A 117
MET A  45
 None
 0.96A 3phaA-1vjzA:
2.8		 3phaA-1vjzA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 HIS A 131
VAL A 194
LEU A 172
 None
 0.65A 4m2vA-1vjzA:
undetectable		 4m2vA-1vjzA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 LEU A 291
MET A  33
TYR A 329
 None
 0.83A 4p6xG-1vjzA:
undetectable		 4p6xG-1vjzA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 LEU A  85
ASP A 176
ILE A  67
 None
 0.68A 4xi3D-1vjzA:
undetectable		 4xi3D-1vjzA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		4 / 5 ALA A 109
HIS A  47
ALA A  88
GLU A  99
 None
 0.96A 5a06C-1vjzA:
undetectable
5a06D-1vjzA:
undetectable		 5a06C-1vjzA:
22.54
5a06D-1vjzA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 VAL A 271
THR A 266
ARG A 305
 None
 0.78A 5b2sB-1vjzA:
undetectable		 5b2sB-1vjzA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		3 / 3 VAL A 271
THR A 266
ARG A 305
 None
 0.78A 5b2tB-1vjzA:
undetectable		 5b2tB-1vjzA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1vjz ENDOGLUCANASE
(Thermotoga
maritima) 		5 / 12 ARG A 159
LEU A 136
LEU A  85
ILE A 120
ARG A 122
 None
 1.32A 5uahC-1vjzA:
0.0		 5uahC-1vjzA:
13.04