SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vk5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_B_CHDB1130_0 (FATTY ACID-BINDING PROTEIN)	1vk5	EXPRESSED PROTEIN (Arabidopsis thaliana)	5 / 12	LEU A 90 LEU A 70 LEU A 82 ARG A 128 ILE A 111	None	1.24A	1tw4B-1vk5A: 0.0	1tw4B-1vk5A: 20.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GAN_A_SVRA158_1 (UNCHARACTERIZED PROTEIN AT3G22680)	1vk5	EXPRESSED PROTEIN (Arabidopsis thaliana)	8 / 11	ARG A 41 TYR A 48 GLN A 51 VAL A 52 PRO A 53 PRO A 81 TRP A 140 ILE A 150	CPS A 200 ( 4.6A) CPS A 200 (-4.2A) None None None EDO A 401 (-4.1A) None CPS A 200 (-4.2A)	0.95A	3ganA-1vk5A: 20.4	3ganA-1vk5A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GAN_A_SVRA158_1 (UNCHARACTERIZED PROTEIN AT3G22680)	1vk5	EXPRESSED PROTEIN (Arabidopsis thaliana)	6 / 11	GLN A 51 PRO A 81 TRP A 140 TYR A 146 ILE A 150 ILE A 153	None EDO A 401 (-4.1A) None None CPS A 200 (-4.2A) EDO A 401 (-4.4A)	0.94A	3ganA-1vk5A: 20.4	3ganA-1vk5A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GAN_A_SVRA158_1 (UNCHARACTERIZED PROTEIN AT3G22680)	1vk5	EXPRESSED PROTEIN (Arabidopsis thaliana)	8 / 11	TYR A 48 GLN A 51 VAL A 52 PRO A 53 PRO A 81 TRP A 140 TYR A 146 ILE A 150	CPS A 200 (-4.2A) None None None EDO A 401 (-4.1A) None None CPS A 200 (-4.2A)	0.67A	3ganA-1vk5A: 20.4	3ganA-1vk5A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_A_CELA701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	1vk5	EXPRESSED PROTEIN (Arabidopsis thaliana)	4 / 6	HIS A 112 LEU A 90 ILE A 62 LEU A 122	None	0.91A	3kk6A-1vk5A: undetectable	3kk6A-1vk5A: 14.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TW4_B_CHDB1130_0","FATTY ACID-BINDING PROTEIN","1vk5","EXPRESSED PROTEIN","Arabidopsis thaliana",5,"LEU A  90;LEU A  70;LEU A  82;ARG A 128;ILE A 111","None","1.24A","1tw4B-1vk5A:0.0","1tw4B-1vk5A:20.47"],["3GAN_A_SVRA158_1","UNCHARACTERIZED PROTEIN AT3G22680","1vk5","EXPRESSED PROTEIN","Arabidopsis thaliana",8,"ARG A  41;TYR A  48;GLN A  51;VAL A  52;PRO A  53;PRO A  81;TRP A 140;ILE A 150","CPS A 200 ( 4.6A);CPS A 200 (-4.2A);None;None;None;EDO A 401 (-4.1A);None;CPS A 200 (-4.2A)","0.95A","3ganA-1vk5A:20.4","3ganA-1vk5A:100.00"],["3GAN_A_SVRA158_1","UNCHARACTERIZED PROTEIN AT3G22680","1vk5","EXPRESSED PROTEIN","Arabidopsis thaliana",6,"GLN A  51;PRO A  81;TRP A 140;TYR A 146;ILE A 150;ILE A 153","None;EDO A 401 (-4.1A);None;None;CPS A 200 (-4.2A);EDO A 401 (-4.4A)","0.94A","3ganA-1vk5A:20.4","3ganA-1vk5A:100.00"],["3GAN_A_SVRA158_1","UNCHARACTERIZED PROTEIN AT3G22680","1vk5","EXPRESSED PROTEIN","Arabidopsis thaliana",8,"TYR A  48;GLN A  51;VAL A  52;PRO A  53;PRO A  81;TRP A 140;TYR A 146;ILE A 150","CPS A 200 (-4.2A);None;None;None;EDO A 401 (-4.1A);None;None;CPS A 200 (-4.2A)","0.67A","3ganA-1vk5A:20.4","3ganA-1vk5A:100.00"],["3KK6_A_CELA701_2","PROSTAGLANDIN G\/H SYNTHASE 1","1vk5","EXPRESSED PROTEIN","Arabidopsis thaliana",4,"HIS A 112;LEU A  90;ILE A  62;LEU A 122","None","0.91A","3kk6A-1vk5A:undetectable","3kk6A-1vk5A:14.17"]]