SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vk9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
1vk9 CONSERVED
HYPOTHETICAL PROTEIN
TM1506

(Thermotoga
maritima)
4 / 7 PRO A  72
LEU A  42
LEU A  20
ILE A  75
None
None
UNL  A 201 ( 3.7A)
None
1.04A 3u5jA-1vk9A:
undetectable
3u5jA-1vk9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
1vk9 CONSERVED
HYPOTHETICAL PROTEIN
TM1506

(Thermotoga
maritima)
5 / 12 ILE A 101
ILE A 128
VAL A  39
LEU A  36
VAL A 132
None
0.97A 5mueA-1vk9A:
undetectable
5mueA-1vk9A:
25.86