SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vkz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 GLY A 348
ASN A  35
GLY A  13
ASP A 280
VAL A 363
 None
 1.22A 1ffyA-1vkzA:
undetectable		 1ffyA-1vkzA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		3 / 3 PHE A  22
LEU A 299
MET A 307
 None
 0.86A 1mx1D-1vkzA:
3.2		 1mx1D-1vkzA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 5 ILE A 344
ARG A  40
LEU A 383
PRO A 339
 None
 1.43A 1s8fA-1vkzA:
1.1
1s8fB-1vkzA:
0.3		 1s8fA-1vkzA:
15.55
1s8fB-1vkzA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 VAL A  62
GLU A  15
TYR A  32
HIS A  16
ARG A  40
 None
 1.22A 2cl5B-1vkzA:
3.7		 2cl5B-1vkzA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		3 / 3 VAL A 310
VAL A 295
ASP A 280
 None
 0.74A 2fumD-1vkzA:
undetectable		 2fumD-1vkzA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 7 THR A 109
VAL A 175
ASP A 177
VAL A 114
 None
 1.02A 2qbnA-1vkzA:
undetectable		 2qbnA-1vkzA:
22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		6 / 8 ASP A 204
TYR A 259
ASN A 275
ARG A 277
GLY A 279
GLU A 282
 None
 1.08A 2ys6A-1vkzA:
45.3		 2ys6A-1vkzA:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		6 / 8 TYR A 259
ASN A 275
ARG A 277
GLY A 279
PRO A 281
GLU A 282
 None
 0.71A 2ys6A-1vkzA:
45.3		 2ys6A-1vkzA:
39.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 VAL A  62
GLU A  15
TYR A  32
HIS A  16
ARG A  40
 None
 1.21A 2zvjA-1vkzA:
3.6		 2zvjA-1vkzA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_0
(CATECHOL
O-METHYLTRANSFERASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 VAL A  62
GLU A  15
TYR A  32
HIS A  16
ARG A  40
 None
 1.27A 3a7eA-1vkzA:
3.5		 3a7eA-1vkzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 10 GLY A 106
THR A 109
ILE A 271
LEU A 239
THR A 243
 None
 1.42A 3bexE-1vkzA:
undetectable
3bexF-1vkzA:
undetectable		 3bexE-1vkzA:
21.77
3bexF-1vkzA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 11 LEU A 239
THR A 243
GLY A 106
THR A 109
ILE A 271
 None
 1.42A 3bf1C-1vkzA:
undetectable
3bf1D-1vkzA:
undetectable		 3bf1C-1vkzA:
21.77
3bf1D-1vkzA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 10 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.31A 3fhjA-1vkzA:
2.2		 3fhjA-1vkzA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 10 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.31A 3fhjB-1vkzA:
2.0		 3fhjB-1vkzA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.29A 3fi0A-1vkzA:
2.3		 3fi0A-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.29A 3fi0F-1vkzA:
undetectable		 3fi0F-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.32A 3fi0H-1vkzA:
2.2		 3fi0H-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.32A 3fi0L-1vkzA:
undetectable		 3fi0L-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.35A 3fi0M-1vkzA:
undetectable		 3fi0M-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.28A 3fi0N-1vkzA:
2.4		 3fi0N-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A 221
VAL A 320
HIS A 365
ASP A 318
VAL A 202
 None
 1.28A 3fi0R-1vkzA:
2.4		 3fi0R-1vkzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		6 / 12 TYR A 326
ASN A  44
GLY A  13
ALA A 347
SER A  11
GLY A  34
 None
 1.48A 3hs6B-1vkzA:
undetectable		 3hs6B-1vkzA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 4 ASP A 353
GLY A 354
LYS A 352
GLU A 351
 None
 1.11A 3hznD-1vkzA:
undetectable		 3hznD-1vkzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		3 / 3 PHE A 257
TYR A 302
LEU A  91
 None
 0.77A 3sueB-1vkzA:
undetectable		 3sueB-1vkzA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 ASP A 280
ALA A 347
ASN A  35
ILE A 398
ARG A 362
 None
 1.21A 3wemA-1vkzA:
undetectable		 3wemA-1vkzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 ASP A 280
ALA A 347
ASN A  35
ILE A 398
ARG A 362
 None
 1.21A 3wenA-1vkzA:
undetectable		 3wenA-1vkzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 ASP A 280
ALA A 347
ASN A  35
ILE A 398
ARG A 362
 None
 1.22A 3weoA-1vkzA:
undetectable		 3weoA-1vkzA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 8 ILE A  18
ILE A  61
PHE A  82
GLY A 301
 None
 0.81A 4hb6A-1vkzA:
undetectable		 4hb6A-1vkzA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 8 ILE A  18
ILE A  61
PHE A  82
GLY A 301
 None
 0.67A 4hb8A-1vkzA:
undetectable		 4hb8A-1vkzA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 8 ILE A  18
ILE A  61
PHE A  82
GLY A 301
 None
 0.86A 4hdlA-1vkzA:
undetectable		 4hdlA-1vkzA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 GLY A  19
GLU A  15
ILE A 286
MET A 188
THR A 283
 None
 1.37A 4x3mA-1vkzA:
2.9		 4x3mA-1vkzA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 6 ARG A 362
ASP A 280
VAL A 319
ASP A 318
 None
 1.20A 4xqeA-1vkzA:
3.9		 4xqeA-1vkzA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 6 ARG A 362
ASP A 280
VAL A 319
ASP A 318
 None
 1.19A 4xqeB-1vkzA:
5.7		 4xqeB-1vkzA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 7 VAL A  62
LEU A 278
VAL A 287
THR A 283
 None
 0.78A 5e4dA-1vkzA:
undetectable
5e4dB-1vkzA:
undetectable		 5e4dA-1vkzA:
19.32
5e4dB-1vkzA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		3 / 3 LYS A 206
ASP A 204
ARG A 362
 None
 0.97A 5jwaA-1vkzA:
3.5
5jwaH-1vkzA:
3.8		 5jwaA-1vkzA:
21.98
5jwaH-1vkzA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 12 HIS A 365
LEU A 364
ALA A 347
THR A 393
ARG A 395
 None
 1.00A 5nd3B-1vkzA:
undetectable		 5nd3B-1vkzA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		3 / 3 ARG A 377
ARG A 395
ARG A 203
 None
 0.95A 5vcgA-1vkzA:
undetectable		 5vcgA-1vkzA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 5 MET A 188
ASN A 192
VAL A 197
LEU A 199
 None
 0.90A 5xdhB-1vkzA:
0.2		 5xdhB-1vkzA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 5 MET A 188
ASN A 195
VAL A 197
LEU A 199
 None
 1.26A 5xdhB-1vkzA:
0.2		 5xdhB-1vkzA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 5 MET A 188
ASN A 192
VAL A 197
LEU A 199
 None
 0.85A 5xdhD-1vkzA:
0.1		 5xdhD-1vkzA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 5 MET A 188
ASN A 195
VAL A 197
LEU A 199
 None
 1.09A 5xdhD-1vkzA:
0.1		 5xdhD-1vkzA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		3 / 3 GLY A 279
THR A 283
GLU A 284
 None
 0.58A 6b58A-1vkzA:
3.8		 6b58A-1vkzA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 9 LEU A 278
GLY A  65
ILE A  63
PHE A 294
ILE A  18
 None
 1.28A 6ebpA-1vkzA:
undetectable		 6ebpA-1vkzA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		5 / 10 LEU A 278
GLY A  65
ILE A  63
PHE A 294
ILE A  18
 None
 1.26A 6ebpC-1vkzA:
undetectable		 6ebpC-1vkzA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 5 LEU A 338
LEU A 321
PRO A 281
ARG A  14
 None
 0.89A 6ew0F-1vkzA:
1.4		 6ew0F-1vkzA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 6 LEU A 338
LEU A 321
PRO A 281
ARG A  14
 None
 0.89A 6ew0G-1vkzA:
1.4		 6ew0G-1vkzA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE
(Thermotoga
maritima) 		4 / 6 GLY A 279
THR A 283
ILE A  18
PHE A  22
 None
 0.88A 6f8cA-1vkzA:
undetectable		 6f8cA-1vkzA:
11.19