SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		3 / 3 ASP A  71
ASP A  75
ASP A  98
 None
 0.76A 1eizA-1vl5A:
12.8		 1eizA-1vl5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		3 / 3 ASP A  71
ASP A  75
ASP A  98
 None
 0.78A 1ej0A-1vl5A:
13.0		 1ej0A-1vl5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		4 / 6 PHE A 199
GLU A 248
GLY A 247
SER A 147
 None
 1.15A 1kqbC-1vl5A:
undetectable
1kqbD-1vl5A:
undetectable		 1kqbC-1vl5A:
21.45
1kqbD-1vl5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ALA A  50
GLY A  52
ALA A  99
HIS A 120
PHE A 121
 None
 1.01A 1ve3A-1vl5A:
20.4		 1ve3A-1vl5A:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ALA A  50
GLY A  52
ALA A  99
HIS A 120
PHE A 121
 None
 1.00A 1ve3B-1vl5A:
21.3		 1ve3B-1vl5A:
26.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GLU_A_SAMA301_0
(YCGJ)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		6 / 12 GLY A  52
HIS A  55
ASP A  71
ALA A  99
ARG A 115
HIS A 120
 None
 0.76A 2gluA-1vl5A:
31.7		 2gluA-1vl5A:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GLU_B_SAMB302_0
(YCGJ)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		7 / 12 GLY A  52
HIS A  55
ALA A  99
ARG A 115
ALA A 117
HIS A 120
PHE A 121
 None
 0.40A 2gluB-1vl5A:
31.7		 2gluB-1vl5A:
34.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GLU_B_SAMB302_0
(YCGJ)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 GLY A  52
THR A  73
ALA A  99
ALA A 117
PHE A 121
 None
 0.87A 2gluB-1vl5A:
31.7		 2gluB-1vl5A:
34.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 LEU A  34
MET A  35
ILE A  84
LEU A 141
VAL A  46
 None
 1.13A 2po5A-1vl5A:
2.5		 2po5A-1vl5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		4 / 7 ALA A  50
GLY A  52
ASP A  71
ASP A  98
 None
 0.52A 2uyqA-1vl5A:
12.2		 2uyqA-1vl5A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		3 / 3 GLU A 162
HIS A 170
HIS A 120
 None
 0.87A 3co4A-1vl5A:
undetectable		 3co4A-1vl5A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		3 / 3 ASP A  71
ASP A  75
ASP A  98
 None
 0.73A 3douA-1vl5A:
12.8		 3douA-1vl5A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		3 / 3 GLY A  52
ASP A  71
ASP A  98
 None
 0.40A 3ou7C-1vl5A:
16.7		 3ou7C-1vl5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ALA A  50
GLY A  52
LEU A  72
ASP A  98
HIS A 120
 None
 0.83A 3pfgA-1vl5A:
19.5		 3pfgA-1vl5A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ALA A  59
HIS A  89
GLY A  54
HIS A  55
ALA A 117
 None
 1.25A 3tm4A-1vl5A:
11.2		 3tm4A-1vl5A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ALA A  59
HIS A  89
GLY A  54
HIS A  55
ALA A 117
 None
 1.24A 3tm4B-1vl5A:
11.1		 3tm4B-1vl5A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		6 / 12 GLY A  52
LEU A  72
ASP A  98
ALA A  99
ARG A 115
HIS A 120
 None
 0.97A 4krhA-1vl5A:
12.6		 4krhA-1vl5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 GLY A  52
LEU A  72
ALA A  99
ARG A 115
HIS A 120
 None
 0.86A 4krhB-1vl5A:
13.0		 4krhB-1vl5A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ILE A 111
ALA A 131
ARG A 133
LEU A 135
PHE A  60
 None
 1.26A 4zo1X-1vl5A:
undetectable		 4zo1X-1vl5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		4 / 4 ASP A  48
GLY A  52
ASP A  71
ASP A  98
 None
 0.69A 5e72A-1vl5A:
18.1		 5e72A-1vl5A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		5 / 12 ALA A  50
GLY A  52
LEU A  72
ALA A  99
PRO A 122
 None
 0.56A 5jglB-1vl5A:
18.4		 5jglB-1vl5A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		3 / 3 LYS A 174
TRP A 173
SER A 176
 None
 1.33A 5nwwA-1vl5A:
undetectable		 5nwwA-1vl5A:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1vl5 UNKNOWN CONSERVED
PROTEIN BH2331
(Bacillus
halodurans) 		4 / 8 LEU A 251
VAL A 144
THR A 113
VAL A  56
 None
 1.10A 6cp4A-1vl5A:
undetectable		 6cp4A-1vl5A:
20.09