SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A  37
VAL A  69
ILE A  47
THR A  25
ILE A  23
 None
 0.96A 1c6yA-1vl7A:
undetectable		 1c6yA-1vl7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 6 ARG A  85
ILE A 141
GLY A 142
ALA A  83
 None
 0.93A 1wmqA-1vl7A:
undetectable		 1wmqA-1vl7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 6 ARG A  85
ILE A 141
GLY A 142
ALA A  83
 None
 0.92A 1wmqB-1vl7A:
undetectable		 1wmqB-1vl7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 6 ARG A  85
ILE A 141
GLY A 142
ALA A  83
 None
 0.94A 1wpuA-1vl7A:
undetectable		 1wpuA-1vl7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 6 ARG A  85
ILE A 141
GLY A 142
ALA A  83
 None
 0.93A 1wpuB-1vl7A:
undetectable		 1wpuB-1vl7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		3 / 3 ASP A  73
PHE A  14
ARG A  85
 None
 0.91A 2a3aA-1vl7A:
undetectable		 2a3aA-1vl7A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 8 PHE A  39
ILE A  41
PHE A  71
GLY A  13
 None
 0.96A 2qwxA-1vl7A:
undetectable
2qwxB-1vl7A:
undetectable		 2qwxA-1vl7A:
21.67
2qwxB-1vl7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A  21
VAL A  69
TYR A  48
ILE A  49
ILE A  41
 EDO  A 147 ( 4.9A)
None
None
None
None
 1.17A 3retA-1vl7A:
undetectable
3retB-1vl7A:
undetectable		 3retA-1vl7A:
22.64
3retB-1vl7A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 8 PHE A  39
ILE A  41
PHE A  71
GLY A  13
 None
 0.94A 4qogA-1vl7A:
undetectable
4qogB-1vl7A:
undetectable		 4qogA-1vl7A:
21.67
4qogB-1vl7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vl7 HYPOTHETICAL PROTEIN
ALR5027
(Nostoc
sp.
PCC
7120) 		4 / 6 ILE A  15
LEU A  87
PHE A  71
THR A 133
 None
 0.91A 5b1aN-1vl7A:
undetectable
5b1aW-1vl7A:
undetectable		 5b1aN-1vl7A:
13.81
5b1aW-1vl7A:
14.65