SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vla'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA508_0 (CHORISMATE SYNTHASE)	1vla	HYDROPEROXIDE RESISTANCE PROTEIN OSMC (Thermotoga maritima)	4 / 5	LEU A 22 ASP A 24 ALA A 35 ILE A 6	None	0.96A	2qhfA-1vlaA: undetectable	2qhfA-1vlaA: 16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB200_0 (ILEAL BILE ACID-BINDING PROTEIN)	1vla	HYDROPEROXIDE RESISTANCE PROTEIN OSMC (Thermotoga maritima)	4 / 5	PRO A 102 VAL A 63 THR A 50 GLY A 51	None	1.21A	3elzB-1vlaA: undetectable	3elzB-1vlaA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS4_A_AZMA702_1 (CARBONIC ANHYDRASE 2)	1vla	HYDROPEROXIDE RESISTANCE PROTEIN OSMC (Thermotoga maritima)	4 / 7	VAL A 106 LYS A 103 TYR A 136 GLU A 133	None	1.19A	3hs4A-1vlaA: undetectable	3hs4A-1vlaA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_C_ACTC4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	1vla	HYDROPEROXIDE RESISTANCE PROTEIN OSMC (Thermotoga maritima)	4 / 4	GLY A 45 GLY A 48 THR A 50 LEU A 91	None	0.89A	3si7C-1vlaA: undetectable 3si7D-1vlaA: undetectable	3si7C-1vlaA: 18.35 3si7D-1vlaA: 18.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QHF_A_ACTA508_0","CHORISMATE SYNTHASE","1vla","HYDROPEROXIDE RESISTANCE PROTEIN OSMC","Thermotoga maritima",4,"LEU A  22;ASP A  24;ALA A  35;ILE A   6","None","0.96A","2qhfA-1vlaA:undetectable","2qhfA-1vlaA:16.28"],["3ELZ_B_CHDB200_0","ILEAL BILE ACID-BINDING PROTEIN","1vla","HYDROPEROXIDE RESISTANCE PROTEIN OSMC","Thermotoga maritima",4,"PRO A 102;VAL A  63;THR A  50;GLY A  51","None","1.21A","3elzB-1vlaA:undetectable","3elzB-1vlaA:21.82"],["3HS4_A_AZMA702_1","CARBONIC ANHYDRASE 2","1vla","HYDROPEROXIDE RESISTANCE PROTEIN OSMC","Thermotoga maritima",4,"VAL A 106;LYS A 103;TYR A 136;GLU A 133","None","1.19A","3hs4A-1vlaA:undetectable","3hs4A-1vlaA:20.38"],["3SI7_C_ACTC4_0","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","1vla","HYDROPEROXIDE RESISTANCE PROTEIN OSMC","Thermotoga maritima",4,"GLY A  45;GLY A  48;THR A  50;LEU A  91","None","0.89A","3si7C-1vlaA:undetectable;3si7D-1vlaA:undetectable","3si7C-1vlaA:18.35;3si7D-1vlaA:18.35"]]