SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 7 GLY A 296
ALA A 183
THR A 291
ILE A 298
 None
 0.83A 1gtnA-1vliA:
undetectable
1gtnK-1vliA:
undetectable		 1gtnA-1vliA:
13.01
1gtnK-1vliA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 8 GLY A 296
ALA A 183
THR A 291
ILE A 298
 None
 0.82A 1gtnE-1vliA:
undetectable
1gtnF-1vliA:
undetectable		 1gtnE-1vliA:
13.01
1gtnF-1vliA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 ALA A  21
LEU A  37
ALA A  41
LEU A 257
PRO A 254
 None
 0.89A 1mjqC-1vliA:
undetectable
1mjqD-1vliA:
undetectable		 1mjqC-1vliA:
16.96
1mjqD-1vliA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 ALA A  21
LEU A  37
ALA A  41
LEU A 257
PRO A 254
 None
 0.89A 1mjqI-1vliA:
undetectable
1mjqJ-1vliA:
undetectable		 1mjqI-1vliA:
16.96
1mjqJ-1vliA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 ALA A 230
VAL A 226
ALA A 225
HIS A 180
 None
 1.06A 1q23A-1vliA:
undetectable		 1q23A-1vliA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 THR A 153
SER A 152
LEU A 232
VAL A  11
PHE A   4
 None
 1.47A 1q23D-1vliA:
undetectable
1q23E-1vliA:
undetectable		 1q23D-1vliA:
20.41
1q23E-1vliA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 10 THR A 153
SER A 152
LEU A 232
VAL A  11
PHE A   4
 None
 1.49A 1q23E-1vliA:
undetectable		 1q23E-1vliA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 ALA A 230
VAL A 226
ALA A 225
HIS A 180
 None
 1.15A 1q23F-1vliA:
undetectable		 1q23F-1vliA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 ALA A 230
VAL A 226
ALA A 225
HIS A 180
 None
 1.17A 1q23K-1vliA:
undetectable		 1q23K-1vliA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 8 GLY A 296
ALA A 183
THR A 291
ILE A 298
 None
 0.81A 1utdI-1vliA:
undetectable
1utdJ-1vliA:
undetectable		 1utdI-1vliA:
13.01
1utdJ-1vliA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 8 GLY A 296
ALA A 183
THR A 291
ILE A 298
 None
 0.81A 1utdJ-1vliA:
undetectable
1utdK-1vliA:
undetectable		 1utdJ-1vliA:
13.01
1utdK-1vliA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		6 / 12 GLY A 315
ALA A 349
ASP A 363
ILE A 359
ALA A 310
ILE A 312
 None
 1.46A 2nmzA-1vliA:
undetectable		 2nmzA-1vliA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 11 ALA A  21
ILE A  38
ALA A  44
ALA A  42
VAL A 103
 None
 1.05A 2qhfA-1vliA:
undetectable		 2qhfA-1vliA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 7 ALA A 115
GLY A 113
ASP A 116
LEU A 145
ARG A 144
 None
 1.30A 2uyqA-1vliA:
undetectable		 2uyqA-1vliA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 GLY A 229
ILE A 209
ALA A 221
LEU A 194
LEU A 284
 None
 0.96A 2yqzA-1vliA:
undetectable		 2yqzA-1vliA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 GLY A 229
ILE A 209
ALA A 221
LEU A 194
LEU A 284
 None
 0.96A 2yqzB-1vliA:
undetectable		 2yqzB-1vliA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 LEU A 106
ALA A 177
VAL A 142
ILE A  20
MET A 179
 None
 1.15A 3czhB-1vliA:
undetectable		 3czhB-1vliA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		3 / 3 GLU A 163
LEU A 136
LEU A 343
 None
 0.78A 3ohtB-1vliA:
undetectable		 3ohtB-1vliA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 8 ILE A 197
ILE A 233
GLU A 220
VAL A 279
 None
 0.88A 3ua5A-1vliA:
undetectable		 3ua5A-1vliA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 5 HIS A 214
LEU A 232
LEU A 106
ASP A  47
 ZN  A 374 (-3.5A)
None
None
None
 1.29A 4aqlA-1vliA:
3.8		 4aqlA-1vliA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 7 GLY A 358
THR A 308
ILE A 312
PHE A 318
 None
 0.80A 4ejjA-1vliA:
undetectable		 4ejjA-1vliA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 6 PHE A 340
ILE A 306
PHE A 318
ASN A 322
 None
 1.33A 4o7gB-1vliA:
undetectable		 4o7gB-1vliA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 1.01A 5n0rA-1vliA:
undetectable		 5n0rA-1vliA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 0.99A 5n0sA-1vliA:
undetectable		 5n0sA-1vliA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 5 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 1.00A 5n0tA-1vliA:
undetectable		 5n0tA-1vliA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 0.98A 5n0wA-1vliA:
undetectable		 5n0wA-1vliA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 5 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 0.99A 5n0wB-1vliA:
undetectable		 5n0wB-1vliA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 1.04A 5n0xA-1vliA:
undetectable		 5n0xA-1vliA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 5 SER A 130
ALA A 129
GLN A  52
THR A 108
 None
 1.03A 5n4iA-1vliA:
undetectable		 5n4iA-1vliA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 6 ARG A 265
GLY A 263
THR A 267
GLU A 268
 None
 0.92A 5ny7A-1vliA:
2.3		 5ny7A-1vliA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		5 / 12 PHE A  18
GLU A 268
GLY A  12
PHE A   4
ILE A   6
 None
 1.25A 5tuiB-1vliA:
undetectable		 5tuiB-1vliA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 6 SER A 130
ARG A 327
GLU A 132
TYR A 131
 None
 1.45A 5x7pB-1vliA:
undetectable		 5x7pB-1vliA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 6 SER A 130
ARG A 327
GLU A 132
TYR A 131
 None
 1.50A 5x7qA-1vliA:
1.5		 5x7qA-1vliA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 ASP A 363
ILE A 306
PRO A 337
LEU A 335
 None
 1.24A 6mkeB-1vliA:
undetectable		 6mkeB-1vliA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE
(Bacillus
subtilis) 		4 / 4 ASP A 363
ILE A 306
PRO A 337
LEU A 335
 None
 1.26A 6mkeA-1vliA:
undetectable		 6mkeA-1vliA:
13.64