SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vls'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_D_29SD601_2 (ESTROGEN RECEPTOR)	1vls	ASPARTATE RECEPTOR (Salmonella enterica)	3 / 3	LEU A 137 ASP A 142 ILE A 65	None	0.71A	4xi3D-1vlsA: undetectable	4xi3D-1vlsA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJ7_A_ADNA303_1 (5'/3'-NUCLEOTIDASE SURE)	1vls	ASPARTATE RECEPTOR (Salmonella enterica)	5 / 10	GLY A 162 ALA A 100 LEU A 161 LEU A 165 TYR A 127	None	1.20A	4xj7A-1vlsA: undetectable 4xj7B-1vlsA: undetectable	4xj7A-1vlsA: 20.42 4xj7B-1vlsA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XRG_A_AG2A502_1 (HOMOSPERMIDINE SYNTHASE)	1vls	ASPARTATE RECEPTOR (Salmonella enterica)	5 / 12	PRO A 112 VAL A 123 SER A 120 TYR A 168 LEU A 46	None	1.23A	4xrgA-1vlsA: undetectable	4xrgA-1vlsA: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9A_A_AR3A201_1 (PEPTIDYL-TRNA HYDROLASE)	1vls	ASPARTATE RECEPTOR (Salmonella enterica)	4 / 6	ALA A 101 GLN A 131 GLN A 128 ASP A 124	None	1.38A	5y9aA-1vlsA: undetectable	5y9aA-1vlsA: 17.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4XI3_D_29SD601_2","ESTROGEN RECEPTOR","1vls","ASPARTATE RECEPTOR","Salmonella enterica",3,"LEU A 137;ASP A 142;ILE A  65","None","0.71A","4xi3D-1vlsA:undetectable","4xi3D-1vlsA:16.09"],["4XJ7_A_ADNA303_1","5'\/3'-NUCLEOTIDASE SURE;5'\/3'-NUCLEOTIDASE SURE","1vls","ASPARTATE RECEPTOR","Salmonella enterica",5,"GLY A 162;ALA A 100;LEU A 161;LEU A 165;TYR A 127","None","1.20A","4xj7A-1vlsA:undetectable;4xj7B-1vlsA:undetectable","4xj7A-1vlsA:20.42;4xj7B-1vlsA:20.42"],["4XRG_A_AG2A502_1","HOMOSPERMIDINE SYNTHASE","1vls","ASPARTATE RECEPTOR","Salmonella enterica",5,"PRO A 112;VAL A 123;SER A 120;TYR A 168;LEU A  46","None","1.23A","4xrgA-1vlsA:undetectable","4xrgA-1vlsA:16.25"],["5Y9A_A_AR3A201_1","PEPTIDYL-TRNA HYDROLASE","1vls","ASPARTATE RECEPTOR","Salmonella enterica",4,"ALA A 101;GLN A 131;GLN A 128;ASP A 124","None","1.38A","5y9aA-1vlsA:undetectable","5y9aA-1vlsA:17.87"]]