SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vlu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A   2
GLU A 197
ASP A 191
 None
 0.85A 2zthA-1vluA:
6.1		 2zthA-1vluA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A   2
GLU A 197
ASP A 191
 None
 0.86A 3bwmA-1vluA:
3.9		 3bwmA-1vluA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A   2
GLU A 197
ASP A 191
 None
 0.85A 3bwyA-1vluA:
4.2		 3bwyA-1vluA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 178
VAL A 175
LEU A  18
ILE A   7
LEU A 119
 None
 0.96A 3cjtO-1vluA:
4.1		 3cjtO-1vluA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 223
VAL A 413
ILE A  33
LEU A 145
VAL A 120
 None
 0.96A 3sp9B-1vluA:
undetectable		 3sp9B-1vluA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 246
ILE A 266
ILE A 232
ASP A 239
ALA A 238
 None
 1.18A 3uj7A-1vluA:
0.0		 3uj7A-1vluA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 246
ILE A 266
ILE A 232
ASP A 239
ALA A 238
 None
 1.18A 3uj7B-1vluA:
4.1		 3uj7B-1vluA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 128
ILE A 132
LEU A 192
LEU A 119
 None
 0.97A 4l1wA-1vluA:
undetectable		 4l1wA-1vluA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 ILE A 137
VAL A 177
VAL A 175
ARG A  26
 None
 1.18A 4m6tA-1vluA:
undetectable		 4m6tA-1vluA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 128
ILE A 132
LEU A 192
LEU A 119
 None
 0.98A 4xo7A-1vluA:
undetectable		 4xo7A-1vluA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A   2
GLU A 197
ASP A 191
 None
 0.85A 4xudA-1vluA:
4.2		 4xudA-1vluA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 162
ASN A 163
ILE A 166
ILE A 129
 None
 0.54A 5bmvC-1vluA:
undetectable		 5bmvC-1vluA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 162
ASN A 163
ILE A 166
ALA A 167
ILE A 129
 None
 0.56A 5j2tC-1vluA:
undetectable		 5j2tC-1vluA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 SER A   2
ILE A 199
GLU A 197
ASP A 191
 None
 1.06A 5n5dA-1vluA:
undetectable		 5n5dA-1vluA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 6 LYS A 301
VAL A 276
LYS A 272
ILE A 266
 None
 1.25A 5q1sA-1vluA:
undetectable		 5q1sA-1vluA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 LEU A  18
GLY A 140
SER A 139
SER A 136
 None
 1.26A 5uunA-1vluA:
undetectable		 5uunA-1vluA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 1vlu GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 116
ASP A 200
ARG A  12
GLN A 422
 None
 1.19A 5zrfB-1vluA:
undetectable		 5zrfB-1vluA:
22.93