SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vmd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SH9_B_RITB301_1 (POL POLYPROTEIN)	1vmd	METHYLGLYOXAL SYNTHASE (Thermotoga maritima)	4 / 8	ALA A 19 ILE A 82 ILE A 118 ILE A 122	None	0.69A	1sh9A-1vmdA: undetectable	1sh9A-1vmdA: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD9_A_ADNA501_2 (NUPC FAMILY PROTEIN)	1vmd	METHYLGLYOXAL SYNTHASE (Thermotoga maritima)	3 / 3	THR A 52 ASN A 37 PHE A 36	SO4 A 167 (-4.1A) None None	0.65A	4pd9A-1vmdA: undetectable	4pd9A-1vmdA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	1vmd	METHYLGLYOXAL SYNTHASE (Thermotoga maritima)	5 / 12	ILE A 112 ALA A 80 THR A 52 THR A 49 LEU A 109	None None SO4 A 167 (-4.1A) SO4 A 167 (-3.4A) None	1.35A	4qynA-1vmdA: undetectable	4qynA-1vmdA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_A_RTLA201_0 (RETINOL-BINDING PROTEIN 2)	1vmd	METHYLGLYOXAL SYNTHASE (Thermotoga maritima)	5 / 12	ILE A 112 ALA A 80 THR A 52 THR A 49 LEU A 109	None None SO4 A 167 (-4.1A) SO4 A 167 (-3.4A) None	1.37A	4qzuA-1vmdA: undetectable	4qzuA-1vmdA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB5_A_ADNA401_2 (ADENOSINE KINASE)	1vmd	METHYLGLYOXAL SYNTHASE (Thermotoga maritima)	4 / 4	ASN A 37 LEU A 41 SER A 35 LEU A 56	None	1.31A	5kb5A-1vmdA: undetectable	5kb5A-1vmdA: 20.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SH9_B_RITB301_1","POL POLYPROTEIN;POL POLYPROTEIN","1vmd","METHYLGLYOXAL SYNTHASE","Thermotoga maritima",4,"ALA A  19;ILE A  82;ILE A 118;ILE A 122","None","0.69A","1sh9A-1vmdA:undetectable","1sh9A-1vmdA:20.22"],["4PD9_A_ADNA501_2","NUPC FAMILY PROTEIN","1vmd","METHYLGLYOXAL SYNTHASE","Thermotoga maritima",3,"THR A  52;ASN A  37;PHE A  36","SO4 A 167 (-4.1A);None;None","0.65A","4pd9A-1vmdA:undetectable","4pd9A-1vmdA:17.46"],["4QYN_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","1vmd","METHYLGLYOXAL SYNTHASE","Thermotoga maritima",5,"ILE A 112;ALA A  80;THR A  52;THR A  49;LEU A 109","None;None;SO4 A 167 (-4.1A);SO4 A 167 (-3.4A);None","1.35A","4qynA-1vmdA:undetectable","4qynA-1vmdA:18.68"],["4QZU_A_RTLA201_0","RETINOL-BINDING PROTEIN 2","1vmd","METHYLGLYOXAL SYNTHASE","Thermotoga maritima",5,"ILE A 112;ALA A  80;THR A  52;THR A  49;LEU A 109","None;None;SO4 A 167 (-4.1A);SO4 A 167 (-3.4A);None","1.37A","4qzuA-1vmdA:undetectable","4qzuA-1vmdA:18.68"],["5KB5_A_ADNA401_2","ADENOSINE KINASE","1vmd","METHYLGLYOXAL SYNTHASE","Thermotoga maritima",4,"ASN A  37;LEU A  41;SER A  35;LEU A  56","None","1.31A","5kb5A-1vmdA:undetectable","5kb5A-1vmdA:20.71"]]