SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 GLU A  50
TRP A 109
LYS A  57
 None
 1.41A 4k7aA-1vmfA:
undetectable		 4k7aA-1vmfA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 GLU A  79
THR A  42
HIS A  85
 None
ACT  A 135 (-3.1A)
None
 0.70A 4q15A-1vmfA:
undetectable		 4q15A-1vmfA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 GLU A  79
THR A  42
HIS A  85
 None
ACT  A 135 (-3.1A)
None
 0.70A 4q15B-1vmfA:
undetectable		 4q15B-1vmfA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 GLU A  79
THR A  42
HIS A  85
 None
ACT  A 135 (-3.1A)
None
 0.65A 4ydqB-1vmfA:
undetectable		 4ydqB-1vmfA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		5 / 9 ILE A  46
GLY A  92
THR A  90
GLN A  20
LEU A  64
 None
 1.46A 5fhzB-1vmfA:
undetectable		 5fhzB-1vmfA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 THR A   8
GLU A 116
HIS A  41
 None
None
ACT  A 135 (-4.1A)
 0.87A 5xioA-1vmfA:
undetectable		 5xioA-1vmfA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 THR A   8
GLU A 116
HIS A  41
 None
None
ACT  A 135 (-4.1A)
 0.82A 5xiqB-1vmfA:
undetectable		 5xiqB-1vmfA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		3 / 3 THR A   8
GLU A 116
HIS A  41
 None
None
ACT  A 135 (-4.1A)
 0.87A 5xiqD-1vmfA:
undetectable		 5xiqD-1vmfA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 7 ARG A 121
GLU A 116
ASP A 118
GLU A  79
 None
 1.20A 6mn4F-1vmfA:
undetectable		 6mn4F-1vmfA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1vmf HYPOTHETICAL PROTEIN
(Bacillus
halodurans) 		4 / 7 ARG A 121
GLU A 116
ASP A 118
GLU A  79
 None
 1.28A 6mn5B-1vmfA:
undetectable		 6mn5B-1vmfA:
21.48