SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ASP A  21
GLY A 122
ALA A 121
VAL A  18
PRO A  70
 None
 0.90A 1c6yB-1vmiA:
undetectable		 1c6yB-1vmiA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 7 PRO A 291
ALA A 288
TYR A 277
SER A 304
 None
None
None
GOL  A 344 (-3.3A)
 1.02A 1k5qA-1vmiA:
undetectable
1k5qB-1vmiA:
undetectable		 1k5qA-1vmiA:
23.30
1k5qB-1vmiA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A  31
MET A  62
LEU A  65
VAL A  67
HIS A  58
 None
 1.12A 1s9pD-1vmiA:
undetectable		 1s9pD-1vmiA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 8 ALA A 165
GLN A 294
THR A 188
ILE A 181
 None
 0.86A 2dtjA-1vmiA:
undetectable
2dtjB-1vmiA:
undetectable		 2dtjA-1vmiA:
17.98
2dtjB-1vmiA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 ASN A 207
SER A 206
ALA A 253
ASP A 235
 None
 0.92A 3aruA-1vmiA:
undetectable		 3aruA-1vmiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 7 THR A 127
VAL A 130
ILE A 293
SER A 168
 GOL  A 344 (-4.3A)
None
None
GOL  A   1 (-3.4A)
 0.80A 3deuA-1vmiA:
undetectable		 3deuA-1vmiA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 TYR A 286
LEU A 154
VAL A 289
ILE A   2
THR A 193
 None
 1.23A 3frqA-1vmiA:
undetectable		 3frqA-1vmiA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 8 LEU A 140
LEU A 296
GLY A 295
VAL A 169
 None
 0.73A 4c9nA-1vmiA:
undetectable		 4c9nA-1vmiA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 10 ALA A 262
GLY A 236
LEU A 238
ALA A 242
ASP A 241
 None
 1.45A 5ajqB-1vmiA:
undetectable		 5ajqB-1vmiA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 VAL A 318
ALA A 316
ILE A 312
GLN A 310
SER A 308
 None
 1.11A 5hgcA-1vmiA:
undetectable		 5hgcA-1vmiA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 9 ALA A 121
ASP A 302
ILE A 293
GLY A 134
ILE A 137
 None
 1.30A 5kr2A-1vmiA:
undetectable		 5kr2A-1vmiA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 9 ALA A 121
ASP A 302
ILE A 293
GLY A 134
ILE A 137
 None
 1.24A 5kr2C-1vmiA:
undetectable		 5kr2C-1vmiA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 8 VAL A 266
ILE A 181
ALA A 179
VAL A 234
VAL A 199
 None
 1.40A 5l94A-1vmiA:
undetectable		 5l94A-1vmiA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 THR A 193
PRO A 155
ARG A 287
 None
 0.71A 5nd7B-1vmiA:
2.8		 5nd7B-1vmiA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 10 LEU A 202
GLY A 236
VAL A 264
ARG A 198
ALA A 243
 None
 1.13A 5o96E-1vmiA:
2.4
5o96F-1vmiA:
2.1		 5o96E-1vmiA:
22.53
5o96F-1vmiA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE
(Escherichia
coli) 		6 / 12 ILE A 120
HIS A 301
VAL A 111
LEU A  39
ALA A  40
TYR A  33
 None
 1.40A 6djzA-1vmiA:
undetectable		 6djzA-1vmiA:
23.06