SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vmj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 1vmj HYPOTHETICAL PROTEIN
TM0723
(Thermotoga
maritima) 		4 / 7 LEU A  39
MET A 111
LEU A 113
GLU A 117
 None
 1.15A 1linA-1vmjA:
undetectable		 1linA-1vmjA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_A_AZZA1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1vmj HYPOTHETICAL PROTEIN
TM0723
(Thermotoga
maritima) 		5 / 10 GLU A 101
VAL A 103
VAL A  50
ARG A 100
ALA A  43
 None
 1.29A 2jj8A-1vmjA:
0.0		 2jj8A-1vmjA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1vmj HYPOTHETICAL PROTEIN
TM0723
(Thermotoga
maritima) 		4 / 8 PHE A 120
HIS A  60
GLU A  17
ILE A  21
 None
 1.21A 4cx7A-1vmjA:
undetectable
4cx7B-1vmjA:
undetectable		 4cx7A-1vmjA:
15.44
4cx7B-1vmjA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 1vmj HYPOTHETICAL PROTEIN
TM0723
(Thermotoga
maritima) 		5 / 12 GLY A  99
ILE A  52
GLU A 117
ASN A  42
VAL A 102
 None
 1.03A 4fr0A-1vmjA:
undetectable		 4fr0A-1vmjA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 1vmj HYPOTHETICAL PROTEIN
TM0723
(Thermotoga
maritima) 		4 / 6 ASP A  87
ASN A  88
ALA A  89
TYR A  79
 None
NA  A 140 (-2.6A)
None
None
 1.01A 4mdbA-1vmjA:
undetectable		 4mdbA-1vmjA:
23.56