SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 7 LEU A  58
VAL A  78
TYR A  83
GLY A  33
 None
 0.98A 1lweA-1vmoA:
undetectable		 1lweA-1vmoA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 7 GLY A  14
PHE A  87
ILE A 106
PHE A 159
 None
 0.90A 2qmzA-1vmoA:
undetectable
2qmzB-1vmoA:
undetectable		 2qmzA-1vmoA:
18.22
2qmzB-1vmoA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 7 GLY A 120
PHE A  34
ILE A  53
PHE A 108
 None
 0.92A 2qmzA-1vmoA:
undetectable
2qmzB-1vmoA:
undetectable		 2qmzA-1vmoA:
18.22
2qmzB-1vmoA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 4 VAL A  78
ASP A 119
LEU A  50
ARG A  56
 None
 1.15A 2ziaA-1vmoA:
undetectable		 2ziaA-1vmoA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		3 / 3 ARG A  90
THR A 140
THR A  74
 None
 0.58A 3k2hB-1vmoA:
undetectable		 3k2hB-1vmoA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 8 GLY A 120
PHE A  34
ILE A  53
PHE A 108
 None
 0.87A 4fglD-1vmoA:
undetectable		 4fglD-1vmoA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 7 GLY A  14
PHE A  87
ILE A 106
PHE A 159
 None
 0.90A 4fglC-1vmoA:
undetectable		 4fglC-1vmoA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 6 GLY A  14
PHE A  87
ILE A 106
PHE A 159
 None
 1.01A 4qogA-1vmoA:
0.0
4qogB-1vmoA:
0.0		 4qogA-1vmoA:
18.42
4qogB-1vmoA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vmo VITELLINE MEMBRANE
OUTER LAYER PROTEIN
I
(Gallus
gallus) 		4 / 6 GLY A 120
PHE A  34
ILE A  53
PHE A 108
 None
 1.05A 4qogA-1vmoA:
0.0
4qogB-1vmoA:
0.0		 4qogA-1vmoA:
18.42
4qogB-1vmoA:
18.42