SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vp6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1vp6 CYCLIC-NUCLEOTIDE
BINDING DOMAIN OF
MESORHIZOBIUM LOTI
CNG POTASSIUM
CHANNEL
(Mesorhizobium
loti) 		4 / 7 GLY A 259
SER A 279
SER A 281
GLU A 289
 BR  A 360 ( 3.7A)
None
None
None
 0.90A 2c8aB-1vp6A:
undetectable		 2c8aB-1vp6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1vp6 CYCLIC-NUCLEOTIDE
BINDING DOMAIN OF
MESORHIZOBIUM LOTI
CNG POTASSIUM
CHANNEL
(Mesorhizobium
loti) 		4 / 7 GLY A 259
SER A 279
SER A 281
GLU A 289
 BR  A 360 ( 3.7A)
None
None
None
 0.90A 2c8aD-1vp6A:
undetectable		 2c8aD-1vp6A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1vp6 CYCLIC-NUCLEOTIDE
BINDING DOMAIN OF
MESORHIZOBIUM LOTI
CNG POTASSIUM
CHANNEL
(Mesorhizobium
loti) 		4 / 7 GLU A 289
VAL A 282
VAL A 275
ALA A 294
 None
CMP  A 368 (-4.4A)
None
None
 0.91A 3kp6B-1vp6A:
undetectable		 3kp6B-1vp6A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1vp6 CYCLIC-NUCLEOTIDE
BINDING DOMAIN OF
MESORHIZOBIUM LOTI
CNG POTASSIUM
CHANNEL
(Mesorhizobium
loti) 		4 / 7 LEU A 322
LEU A 251
GLU A 246
ILE A 247
 None
 0.80A 3s56B-1vp6A:
undetectable		 3s56B-1vp6A:
24.11