SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vp8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		4 / 6 GLY A  12
ASP A 160
GLY A 125
SER A 156
 None
None
None
FMN  A 500 (-3.7A)
 0.57A 1eswA-1vp8A:
undetectable		 1eswA-1vp8A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		4 / 6 GLY A 158
VAL A 130
ALA A  38
SER A  40
 FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.7A)
FMN  A 500 (-2.7A)
 0.99A 1p6kA-1vp8A:
undetectable		 1p6kA-1vp8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		4 / 7 THR A 113
MET A 137
ILE A  95
SER A 111
 None
FMN  A 500 (-3.6A)
None
None
 1.17A 2xytI-1vp8A:
undetectable		 2xytI-1vp8A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fhjA-1vp8A:
undetectable		 3fhjA-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.18A 3fhjA-1vp8A:
undetectable		 3fhjA-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fhjB-1vp8A:
undetectable		 3fhjB-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.18A 3fhjB-1vp8A:
undetectable		 3fhjB-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.30A 3fhjC-1vp8A:
undetectable		 3fhjC-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.18A 3fhjC-1vp8A:
undetectable		 3fhjC-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fhjD-1vp8A:
undetectable		 3fhjD-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.17A 3fhjD-1vp8A:
undetectable		 3fhjD-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.30A 3fhjE-1vp8A:
undetectable		 3fhjE-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.18A 3fhjE-1vp8A:
undetectable		 3fhjE-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fhjF-1vp8A:
undetectable		 3fhjF-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.18A 3fhjF-1vp8A:
undetectable		 3fhjF-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.28A 3fi0A-1vp8A:
undetectable		 3fi0A-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.14A 3fi0A-1vp8A:
undetectable		 3fi0A-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fi0C-1vp8A:
undetectable		 3fi0C-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.15A 3fi0C-1vp8A:
undetectable		 3fi0C-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fi0D-1vp8A:
undetectable		 3fi0D-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.15A 3fi0D-1vp8A:
undetectable		 3fi0D-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fi0F-1vp8A:
undetectable		 3fi0F-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.09A 3fi0F-1vp8A:
undetectable		 3fi0F-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fi0H-1vp8A:
undetectable		 3fi0H-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.21A 3fi0H-1vp8A:
undetectable		 3fi0H-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 8 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.26A 3fi0I-1vp8A:
undetectable		 3fi0I-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 8 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.12A 3fi0I-1vp8A:
undetectable		 3fi0I-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.29A 3fi0J-1vp8A:
undetectable		 3fi0J-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.14A 3fi0J-1vp8A:
undetectable		 3fi0J-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.15A 3fi0L-1vp8A:
undetectable		 3fi0L-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.12A 3fi0M-1vp8A:
undetectable		 3fi0M-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.27A 3fi0N-1vp8A:
undetectable		 3fi0N-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.16A 3fi0N-1vp8A:
undetectable		 3fi0N-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.28A 3fi0O-1vp8A:
undetectable		 3fi0O-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.16A 3fi0O-1vp8A:
undetectable		 3fi0O-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  58
VAL A  90
 None
 1.25A 3fi0R-1vp8A:
undetectable		 3fi0R-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 142
HIS A 169
ILE A 144
VAL A  90
GLN A  92
 None
 1.18A 3fi0R-1vp8A:
undetectable		 3fi0R-1vp8A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		4 / 5 THR A 113
LEU A  96
GLU A 133
LYS A 129
 None
None
FMN  A 500 (-4.1A)
FMN  A 500 ( 2.8A)
 1.46A 4a3pA-1vp8A:
undetectable		 4a3pA-1vp8A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 165
PRO A 167
LEU A  96
ILE A  95
 None
 0.99A 5ieoA-1vp8A:
undetectable		 5ieoA-1vp8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1vp8 HYPOTHETICAL PROTEIN
AF0103
(Archaeoglobus
fulgidus) 		4 / 6 VAL A  59
THR A  61
LEU A  49
GLU A  17
 None
 0.95A 5tudD-1vp8A:
undetectable		 5tudD-1vp8A:
18.37