SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		5 / 12 GLY A 168
GLY A 166
ASP A 119
ALA A 120
HIS A 161
 None
 0.97A 2gluA-1vpdA:
5.0		 2gluA-1vpdA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		4 / 4 LEU A  92
ILE A   8
ILE A  55
ALA A  56
 None
 0.89A 2i30A-1vpdA:
undetectable		 2i30A-1vpdA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		4 / 4 GLY A 166
GLY A 139
GLY A 163
GLY A 168
 None
 0.56A 3bogC-1vpdA:
undetectable		 3bogC-1vpdA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		4 / 4 GLY A 166
GLY A 139
GLY A 163
GLY A 168
 None
 0.55A 3bogD-1vpdA:
undetectable		 3bogD-1vpdA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		3 / 3 LEU A  22
GLU A  47
ILE A  42
 None
 0.56A 3czhA-1vpdA:
undetectable		 3czhA-1vpdA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		3 / 3 GLY A 124
ILE A 178
VAL A 179
 TLA  A 501 (-3.6A)
None
TLA  A 501 ( 4.7A)
 0.50A 3nv6A-1vpdA:
undetectable		 3nv6A-1vpdA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		5 / 12 GLY A   9
GLY A  14
ILE A  63
LEU A  66
PRO A  67
 None
 0.98A 4gc9A-1vpdA:
3.6		 4gc9A-1vpdA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		5 / 8 GLY A 157
VAL A 136
ALA A 120
MET A  95
ASP A 150
 None
 0.92A 4l9iB-1vpdA:
undetectable		 4l9iB-1vpdA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		4 / 8 LEU A 217
THR A 215
VAL A 179
HIS A 279
 None
None
TLA  A 501 ( 4.7A)
TLA  A 501 (-4.8A)
 0.88A 4qknA-1vpdA:
0.0		 4qknA-1vpdA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1vpd TARTRONATE
SEMIALDEHYDE
REDUCTASE
(Salmonella
enterica) 		4 / 8 PHE A   7
ALA A  46
LEU A  28
GLY A   6
 None
 0.90A 4xk8a-1vpdA:
undetectable		 4xk8a-1vpdA:
18.18