SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vph'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 6 ASP A  62
ILE A  63
LEU A  18
GLU A  54
 None
 0.87A 2ya7A-1vphA:
undetectable		 2ya7A-1vphA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 6 ASP A  62
ILE A  63
LEU A  18
GLU A  54
 None
 0.86A 2ya7B-1vphA:
undetectable		 2ya7B-1vphA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 6 ASP A  62
ILE A  63
LEU A  18
GLU A  54
 None
 0.85A 2ya7D-1vphA:
undetectable		 2ya7D-1vphA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 7 LEU A  40
ILE A  21
ILE A 116
VAL A  25
 None
 0.64A 4ojbA-1vphA:
undetectable		 4ojbA-1vphA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 7 HIS A  79
HIS A  89
LEU A  90
SER A  46
 K  A 138 (-3.5A)
K  A 138 (-3.5A)
None
PO4  A 139 (-2.8A)
 0.87A 5m8rA-1vphA:
undetectable		 5m8rA-1vphA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 8 HIS A  79
HIS A  89
LEU A  90
SER A  46
 K  A 138 (-3.5A)
K  A 138 (-3.5A)
None
PO4  A 139 (-2.8A)
 0.90A 5m8rB-1vphA:
undetectable		 5m8rB-1vphA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 8 HIS A  79
HIS A  89
LEU A  90
SER A  46
 K  A 138 (-3.5A)
K  A 138 (-3.5A)
None
PO4  A 139 (-2.8A)
 0.91A 5m8rC-1vphA:
undetectable		 5m8rC-1vphA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 8 HIS A  79
HIS A  89
LEU A  90
SER A  46
 K  A 138 (-3.5A)
K  A 138 (-3.5A)
None
PO4  A 139 (-2.8A)
 0.93A 5m8rD-1vphA:
undetectable		 5m8rD-1vphA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		4 / 5 LEU A  95
PHE A  94
LEU A 121
PHE A  16
 None
 1.19A 5x1fC-1vphA:
undetectable
5x1fJ-1vphA:
undetectable		 5x1fC-1vphA:
18.39
5x1fJ-1vphA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		3 / 3 THR A  12
GLU A 120
HIS A  45
 None
None
PO4  A 139 (-3.9A)
 0.89A 5xioA-1vphA:
undetectable		 5xioA-1vphA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		3 / 3 THR A  12
GLU A 120
HIS A  45
 None
None
PO4  A 139 (-3.9A)
 0.84A 5xiqB-1vphA:
undetectable		 5xiqB-1vphA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1vph HYPOTHETICAL PROTEIN
SSO2532
(Sulfolobus
solfataricus) 		3 / 3 THR A  12
GLU A 120
HIS A  45
 None
None
PO4  A 139 (-3.9A)
 0.89A 5xiqD-1vphA:
undetectable		 5xiqD-1vphA:
17.23