SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vpi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1vpi PHOSPHOLIPASE A2
INHIBITOR
(Vipera
ammodytes) 		5 / 7 GLY A  30
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
 0.99A 1th6A-1vpiA:
21.3		 1th6A-1vpiA:
54.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1vpi PHOSPHOLIPASE A2
INHIBITOR
(Vipera
ammodytes) 		5 / 12 LEU A   2
GLY A  30
TYR A  52
PRO A  68
LYS A  69
 None
 0.84A 1y4lA-1vpiA:
20.7		 1y4lA-1vpiA:
51.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vpi PHOSPHOLIPASE A2
INHIBITOR
(Vipera
ammodytes) 		5 / 7 GLY A  30
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
 0.99A 2armA-1vpiA:
21.3		 2armA-1vpiA:
54.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vpi PHOSPHOLIPASE A2
INHIBITOR
(Vipera
ammodytes) 		4 / 6 LEU A   2
ALA A  18
ASP A  49
TYR A  52
 None
 0.78A 2dpzA-1vpiA:
21.5		 2dpzA-1vpiA:
54.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 1vpi PHOSPHOLIPASE A2
INHIBITOR
(Vipera
ammodytes) 		3 / 3 GLU A 131
PHE A  46
GLN A 132
 None
 0.95A 3r55A-1vpiA:
undetectable		 3r55A-1vpiA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 1vpi PHOSPHOLIPASE A2
INHIBITOR
(Vipera
ammodytes) 		4 / 5 TYR A  75
ILE A  82
LEU A   2
PHE A   5
 None
 0.94A 5kmdC-1vpiA:
0.1
5kmdD-1vpiA:
undetectable		 5kmdC-1vpiA:
15.86
5kmdD-1vpiA:
15.86