SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UUJ_B_ACTB1077_0 (PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT)	1vpm	ACYL-COA HYDROLASE (Bacillus halodurans)	3 / 3	ARG A 16 TYR A 37 LYS A 33	None	0.68A	1uujB-1vpmA: undetectable	1uujB-1vpmA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6H_A_CXXA802_1 (TRANSPORTER)	1vpm	ACYL-COA HYDROLASE (Bacillus halodurans)	4 / 7	ILE A 38 ARG A 16 ILE A 29 PHE A 64	None	1.03A	2q6hA-1vpmA: undetectable	2q6hA-1vpmA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q72_A_IXXA802_1 (TRANSPORTER)	1vpm	ACYL-COA HYDROLASE (Bacillus halodurans)	4 / 6	ILE A 38 ARG A 16 ILE A 29 PHE A 64	None	1.03A	2q72A-1vpmA: undetectable	2q72A-1vpmA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QB4_A_DSMA802_1 (TRANSPORTER)	1vpm	ACYL-COA HYDROLASE (Bacillus halodurans)	4 / 7	ILE A 38 ARG A 16 ILE A 29 PHE A 64	None	1.04A	2qb4A-1vpmA: undetectable	2qb4A-1vpmA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MJR_D_AC2D601_1 (DEOXYCYTIDINE KINASE)	1vpm	ACYL-COA HYDROLASE (Bacillus halodurans)	4 / 8	GLU A 89 ARG A 150 ARG A 146 ASP A 60	None	0.94A	3mjrD-1vpmA: undetectable	3mjrD-1vpmA: 22.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UUJ_B_ACTB1077_0","PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT","1vpm","ACYL-COA HYDROLASE","Bacillus halodurans",3,"ARG A  16;TYR A  37;LYS A  33","None","0.68A","1uujB-1vpmA:undetectable","1uujB-1vpmA:20.24"],["2Q6H_A_CXXA802_1","TRANSPORTER","1vpm","ACYL-COA HYDROLASE","Bacillus halodurans",4,"ILE A  38;ARG A  16;ILE A  29;PHE A  64","None","1.03A","2q6hA-1vpmA:undetectable","2q6hA-1vpmA:14.34"],["2Q72_A_IXXA802_1","TRANSPORTER","1vpm","ACYL-COA HYDROLASE","Bacillus halodurans",4,"ILE A  38;ARG A  16;ILE A  29;PHE A  64","None","1.03A","2q72A-1vpmA:undetectable","2q72A-1vpmA:14.34"],["2QB4_A_DSMA802_1","TRANSPORTER","1vpm","ACYL-COA HYDROLASE","Bacillus halodurans",4,"ILE A  38;ARG A  16;ILE A  29;PHE A  64","None","1.04A","2qb4A-1vpmA:undetectable","2qb4A-1vpmA:14.34"],["3MJR_D_AC2D601_1","DEOXYCYTIDINE KINASE","1vpm","ACYL-COA HYDROLASE","Bacillus halodurans",4,"GLU A  89;ARG A 150;ARG A 146;ASP A  60","None","0.94A","3mjrD-1vpmA:undetectable","3mjrD-1vpmA:22.57"]]