SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		3 / 3 THR W 143
GLU W  37
ASP W  39
 None
None
C  0 946 ( 4.6A)
 0.82A 1nt2A-1vq7W:
undetectable		 1nt2A-1vq7W:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		5 / 9 LEU W 100
THR W  88
VAL W  79
ILE W  93
VAL W  84
 None
 1.32A 2l8mA-1vq7W:
undetectable		 2l8mA-1vq7W:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		5 / 8 LEU W 138
ALA W  53
GLY W 136
GLY W 145
ASP W 142
 None
 1.47A 2yfxA-1vq7W:
undetectable		 2yfxA-1vq7W:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		5 / 12 LEU W 101
SER W  58
LEU W  34
ALA W  53
HIS W   2
 None
 1.35A 3ou7C-1vq7W:
undetectable		 3ou7C-1vq7W:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		4 / 5 VAL W   5
LEU W 149
ILE W 146
VAL W  65
 None
 0.96A 4a9kB-1vq7W:
undetectable		 4a9kB-1vq7W:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		4 / 8 THR W  88
LEU W 112
VAL W  79
VAL W  84
 None
 1.00A 4em2A-1vq7W:
undetectable		 4em2A-1vq7W:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		4 / 9 CYH W  32
ALA W  70
LEU W  62
LEU W 100
 None
 0.99A 4xtaA-1vq7W:
undetectable		 4xtaA-1vq7W:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		4 / 6 VAL W  65
LEU W  66
CYH W  32
LEU W  34
 None
 1.25A 5hrqB-1vq7W:
undetectable
5hrqI-1vq7W:
undetectable
5hrqJ-1vq7W:
undetectable		 5hrqB-1vq7W:
11.89
5hrqI-1vq7W:
7.86
5hrqJ-1vq7W:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		4 / 5 ILE W  26
LEU W 150
HIS W   2
VAL W  35
 None
 1.10A 5jmnB-1vq7W:
undetectable		 5jmnB-1vq7W:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		5 / 12 ILE W 146
GLY W 145
VAL W 132
ALA W   3
VAL W   5
 None
 1.10A 5n0wA-1vq7W:
undetectable		 5n0wA-1vq7W:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		3 / 3 HIS W  87
GLU W  86
TRP W  83
 None
 0.89A 5odiD-1vq7W:
undetectable		 5odiD-1vq7W:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		3 / 3 HIS W  87
GLU W  86
TRP W  83
 None
 0.99A 5odqD-1vq7W:
undetectable		 5odqD-1vq7W:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		3 / 3 HIS W  87
GLU W  86
TRP W  83
 None
 0.87A 5odrD-1vq7W:
undetectable		 5odrD-1vq7W:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		4 / 8 GLY W 124
GLN W 137
VAL W  29
VAL W 128
 U  01096 ( 3.1A)
None
G  01087 ( 4.5A)
A  01098 ( 3.7A)
 0.85A 6czmD-1vq7W:
undetectable
6czmF-1vq7W:
undetectable		 6czmD-1vq7W:
19.94
6czmF-1vq7W:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1vq7 50S RIBOSOMAL
PROTEIN L30P
(Haloarcula
marismortui) 		5 / 7 VAL W  35
ILE W  26
GLY W 127
ARG W  42
ALA W  53
 None
None
A  01098 ( 3.1A)
None
None
 1.17A 6hd6B-1vq7W:
undetectable		 6hd6B-1vq7W:
19.72