SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vqs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IHI_A_IU5A326_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		5 / 10 TYR A   8
VAL A  22
ILE A  27
TRP A  55
LEU A  70
 None
 1.43A 1ihiA-1vqsA:
0.0		 1ihiA-1vqsA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		5 / 10 ARG A  67
VAL A  52
ILE A  51
TYR A  18
ILE A  83
 None
 1.42A 1q6iB-1vqsA:
undetectable		 1q6iB-1vqsA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		5 / 10 ARG A  67
VAL A  52
ILE A  51
TYR A  18
ILE A  83
 None
 1.42A 3ihzA-1vqsA:
undetectable		 3ihzA-1vqsA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		5 / 11 ARG A  67
VAL A  52
ILE A  51
TYR A  18
ILE A  83
 None
 1.44A 3o5rA-1vqsA:
undetectable		 3o5rA-1vqsA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		5 / 10 ARG A  67
VAL A  52
ILE A  51
TYR A  18
ILE A  83
 None
 1.46A 3uf8A-1vqsA:
undetectable		 3uf8A-1vqsA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		3 / 3 LYS A  96
HIS A  -4
HIS A   0
 None
 0.88A 5oexA-1vqsA:
undetectable		 5oexA-1vqsA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		3 / 3 LYS A  96
HIS A  -4
HIS A   0
 None
 0.94A 5oexB-1vqsA:
undetectable		 5oexB-1vqsA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		3 / 3 LYS A  96
HIS A  -4
HIS A   0
 None
 0.92A 5oexC-1vqsA:
undetectable		 5oexC-1vqsA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1vqs HYPOTHETICAL PROTEIN
AGR_L_1239
(Agrobacterium
fabrum) 		3 / 3 LYS A  96
HIS A  -4
HIS A   0
 None
 0.86A 5oexD-1vqsA:
undetectable		 5oexD-1vqsA:
13.08