SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		4 / 6 LEU A  83
MET A  15
LEU A  19
HIS A  53
 None
 1.14A 1errB-1vqyA:
undetectable		 1errB-1vqyA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		4 / 8 ILE A  10
LEU A  86
GLU A  17
LEU A  83
 None
 0.85A 1eupA-1vqyA:
0.0		 1eupA-1vqyA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IHI_A_IU5A326_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		5 / 10 TYR A   8
VAL A  22
ILE A  27
TRP A  55
LEU A  70
 None
 1.39A 1ihiA-1vqyA:
0.0		 1ihiA-1vqyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		4 / 5 LEU A  83
MET A  15
LEU A  19
HIS A  53
 None
 1.15A 2qxsA-1vqyA:
undetectable		 2qxsA-1vqyA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		4 / 5 LEU A  83
MET A  15
LEU A  19
HIS A  53
 None
 1.16A 2qxsB-1vqyA:
undetectable		 2qxsB-1vqyA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		3 / 3 TYR A   8
TYR A  40
GLU A   4
 None
 0.95A 3pfgA-1vqyA:
undetectable		 3pfgA-1vqyA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1vqy HYPOTHETICAL PROTEIN
AGR_PAT_315
(Agrobacterium
fabrum) 		4 / 6 GLU A  88
ILE A  10
GLU A   5
HIS A  53
 None
 1.02A 4ejwB-1vqyA:
undetectable		 4ejwB-1vqyA:
22.56