SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vr8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RL8_A_RITA9001_2 (PROTEASE RETROPEPSIN)	1vr8	GTP BINDING REGULATOR (Thermotoga maritima)	6 / 12	LEU A 38 ALA A 64 ASP A 47 ILE A 131 ALA A 34 ILE A 35	None	1.42A	1rl8B-1vr8A: undetectable	1rl8B-1vr8A: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KM6_A_EAAA222_1 (GLUTATHIONE S-TRANSFERASE P)	1vr8	GTP BINDING REGULATOR (Thermotoga maritima)	5 / 10	PHE A 141 GLY A 71 VAL A 142 ASN A 136 GLY A 137	None None GOL A 4 (-4.5A) None None	1.32A	3km6A-1vr8A: undetectable	3km6A-1vr8A: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW8_C_FK5C201_1 (FK506-BINDING PROTEIN 1)	1vr8	GTP BINDING REGULATOR (Thermotoga maritima)	5 / 10	VAL A 132 ILE A 131 TYR A 54 LEU A 90 PHE A 111	None None GOL A 5 ( 4.2A) None None	0.95A	5hw8C-1vr8A: undetectable 5hw8H-1vr8A: undetectable	5hw8C-1vr8A: 23.65 5hw8H-1vr8A: 23.65