SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vrb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		5 / 10 LEU A 233
LEU A 235
GLN A 155
HIS A 224
PHE A 142
 None
None
None
FE  A 555 (-3.5A)
None
 1.40A 1aqbA-1vrbA:
0.0		 1aqbA-1vrbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		5 / 12 ILE A  13
VAL A  16
MET A 215
LEU A 121
TRP A 113
 None
 1.13A 1wsvA-1vrbA:
1.0		 1wsvA-1vrbA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		5 / 12 LEU A   9
ILE A  13
VAL A  16
LEU A 121
TRP A 113
 None
 1.20A 1wsvA-1vrbA:
1.0		 1wsvA-1vrbA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		5 / 12 ILE A  13
VAL A  16
MET A 215
LEU A 121
TRP A 113
 None
 1.09A 1wsvB-1vrbA:
1.0		 1wsvB-1vrbA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		5 / 12 LEU A   9
ILE A  13
VAL A  16
LEU A 121
TRP A 113
 None
 1.14A 1wsvB-1vrbA:
1.0		 1wsvB-1vrbA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		4 / 7 PRO A 108
ILE A  58
PRO A  44
GLY A  45
 None
 0.97A 2y7kA-1vrbA:
undetectable		 2y7kA-1vrbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		4 / 5 ILE A 114
PRO A  44
VAL A 208
PHE A  40
 None
 1.26A 2ygnA-1vrbA:
undetectable		 2ygnA-1vrbA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		3 / 3 GLY A  35
GLY A 213
THR A 211
 None
 0.32A 3si7B-1vrbA:
undetectable		 3si7B-1vrbA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1vrb PUTATIVE ASPARAGINYL
HYDROXYLASE
(Bacillus
subtilis) 		5 / 12 PHE A  21
PRO A  30
LEU A 164
VAL A 208
ALA A  33
 None
 1.26A 4a84A-1vrbA:
undetectable		 4a84A-1vrbA:
18.82