SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vrn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 10 ALA C  76
GLU C 327
LEU C  65
GLU C  69
GLU C  67
 None
 1.37A 1a29A-1vrnC:
undetectable		 1a29A-1vrnC:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 12 THR C 307
PRO C 143
PRO C 315
VAL C 145
LEU C 282
 None
None
HEM  C 404 (-4.4A)
None
HEM  C 402 ( 4.5A)
 1.44A 1z9hA-1vrnC:
undetectable		 1z9hA-1vrnC:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 12 THR C 307
PRO C 143
PRO C 315
VAL C 145
LEU C 282
 None
None
HEM  C 404 (-4.4A)
None
HEM  C 402 ( 4.5A)
 1.43A 1z9hB-1vrnC:
undetectable		 1z9hB-1vrnC:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 12 THR C 307
PRO C 143
PRO C 315
VAL C 145
LEU C 282
 None
None
HEM  C 404 (-4.4A)
None
HEM  C 402 ( 4.5A)
 1.45A 1z9hC-1vrnC:
undetectable		 1z9hC-1vrnC:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 12 LEU C 154
VAL C 174
ALA C 177
LEU C 176
LEU C 152
 None
 1.15A 2c12C-1vrnC:
undetectable		 2c12C-1vrnC:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 11 LEU C 154
VAL C 174
ALA C 177
LEU C 176
LEU C 152
 None
 1.22A 2c12F-1vrnC:
undetectable		 2c12F-1vrnC:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		4 / 7 TYR C 325
GLU C  69
LEU C 328
TRP C  80
 None
 1.40A 3k8mB-1vrnC:
undetectable		 3k8mB-1vrnC:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 9 TYR C 133
VAL C 274
ILE C 117
ARG C 146
LEU C 316
 None
HEM  C 404 ( 4.9A)
HEM  C 404 ( 4.8A)
None
None
 1.29A 3oxzA-1vrnC:
undetectable		 3oxzA-1vrnC:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		4 / 5 ILE C  77
GLY C  86
CYH C  90
HIS C  91
 HEM  C 402 (-4.1A)
None
HEM  C 401 (-1.8A)
HEM  C 401 (-3.2A)
 1.24A 3r0lD-1vrnC:
undetectable		 3r0lD-1vrnC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		3 / 3 ASP C 304
ARG C 146
ASP C 238
 None
 0.84A 4fp9D-1vrnC:
undetectable		 4fp9D-1vrnC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		3 / 3 ASP C 304
ARG C 146
ASP C 238
 None
 0.87A 4fzvA-1vrnC:
undetectable		 4fzvA-1vrnC:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		4 / 8 LEU C 282
ASN C 278
HIS C 124
ILE C 271
 HEM  C 402 ( 4.5A)
None
HEM  C 404 (-3.2A)
HEM  C 403 (-4.5A)
 1.05A 4ok1A-1vrnC:
undetectable		 4ok1A-1vrnC:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		4 / 8 ALA C 300
GLY C 298
LEU C 294
LEU C 289
 None
None
None
HEM  C 402 ( 4.4A)
 0.76A 4po0A-1vrnC:
undetectable		 4po0A-1vrnC:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		5 / 9 ARG C 272
LEU C 194
ARG C 202
THR C 229
LEU C 232
 HEM  C 403 (-2.9A)
None
HEM  C 403 (-4.1A)
HEM  C 403 ( 4.8A)
None
 1.36A 4ubsA-1vrnC:
undetectable		 4ubsA-1vrnC:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		3 / 3 ASP C 304
ARG C 146
ASP C 238
 None
 0.74A 5zvgA-1vrnC:
undetectable		 5zvgA-1vrnC:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		3 / 3 ASP C 304
ARG C 146
ASP C 238
 None
 0.74A 5zvgB-1vrnC:
undetectable		 5zvgB-1vrnC:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT
(Blastochloris
viridis) 		4 / 6 LYS C  29
ARG C  34
GLU C  33
ALA C  36
 None
 1.16A 6an0A-1vrnC:
undetectable		 6an0A-1vrnC:
22.58