SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 1vsl PROTEIN (INTEGRASE)
(Rous
sarcoma
virus) 		5 / 10 THR A 127
SER A 128
VAL A  96
SER A 124
GLY A 123
 None
None
None
None
ZN  A 200 ( 4.9A)
 1.26A 3ixlA-1vslA:
undetectable		 3ixlA-1vslA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1vsl PROTEIN (INTEGRASE)
(Rous
sarcoma
virus) 		4 / 5 GLN A  59
THR A 120
HIS A 142
LEU A 135
 None
 1.25A 4lvcA-1vslA:
undetectable		 4lvcA-1vslA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1vsl PROTEIN (INTEGRASE)
(Rous
sarcoma
virus) 		4 / 5 GLN A  59
THR A 120
HIS A 142
LEU A 135
 None
 1.25A 4lvcC-1vslA:
undetectable		 4lvcC-1vslA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 1vsl PROTEIN (INTEGRASE)
(Rous
sarcoma
virus) 		3 / 3 HIS A 198
ASN A 197
LEU A 196
 None
 0.76A 6f7lB-1vslA:
undetectable		 6f7lB-1vslA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 1vsl PROTEIN (INTEGRASE)
(Rous
sarcoma
virus) 		4 / 5 GLN A  59
THR A 120
HIS A 142
LEU A 135
 None
 1.25A 6gbnA-1vslA:
undetectable		 6gbnA-1vslA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 1vsl PROTEIN (INTEGRASE)
(Rous
sarcoma
virus) 		4 / 5 GLN A  59
THR A 120
HIS A 142
LEU A 135
 None
 1.24A 6gbnD-1vslA:
undetectable		 6gbnD-1vslA:
15.40