SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vsq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 VAL C 250
LEU C 253
LEU C 294
ILE C 164
ALA C 167
 None
 0.90A 1cqeA-1vsqC:
undetectable		 1cqeA-1vsqC:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 VAL C 250
LEU C 253
LEU C 294
ILE C 164
ALA C 167
 None
 0.91A 1cqeB-1vsqC:
undetectable		 1cqeB-1vsqC:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 VAL C 250
LEU C 253
LEU C 294
ILE C 164
ALA C 167
 None
 0.91A 2aylB-1vsqC:
undetectable		 2aylB-1vsqC:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 VAL C 250
LEU C 253
LEU C 294
ILE C 164
ALA C 167
 None
 0.99A 3kk6A-1vsqC:
undetectable		 3kk6A-1vsqC:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		4 / 5 VAL C 250
LEU C 253
ILE C 164
ALA C 167
 None
 0.76A 3n8yB-1vsqC:
undetectable		 3n8yB-1vsqC:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		3 / 3 LYS C 274
ARG C 271
ASP C 170
 None
 1.25A 3o7wA-1vsqC:
undetectable		 3o7wA-1vsqC:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 ASP C 171
VAL C 281
ILE C 169
VAL C 250
MET C 314
 None
 1.32A 4a84A-1vsqC:
undetectable		 4a84A-1vsqC:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		4 / 7 PRO C 247
VAL C 250
VAL C 263
ILE C 169
 None
 0.67A 5bmvC-1vsqC:
3.1		 5bmvC-1vsqC:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1vsq MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		4 / 6 LYS C 205
VAL C 194
ILE C 192
LYS C 225
 None
 0.98A 5q1sA-1vsqC:
2.9		 5q1sA-1vsqC:
19.06