SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vtm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_A_FFOA1002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 5	TYR P 68 TYR P 70 PHE P 62 PRO P 63	None	1.33A	1dfoB-1vtmP: undetectable	1dfoB-1vtmP: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_B_FFOB2002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 5	TYR P 68 TYR P 70 PHE P 62 PRO P 63	None	1.33A	1dfoA-1vtmP: undetectable	1dfoA-1vtmP: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_C_FFOC3002_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 5	TYR P 68 TYR P 70 PHE P 62 PRO P 63	None	1.33A	1dfoD-1vtmP: undetectable	1dfoD-1vtmP: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_D_FFOD4002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 5	TYR P 68 TYR P 70 PHE P 62 PRO P 63	None	1.34A	1dfoC-1vtmP: undetectable	1dfoC-1vtmP: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 6	TYR P 68 TYR P 70 PHE P 62 PRO P 63	None	1.41A	2vmyA-1vtmP: undetectable	2vmyA-1vtmP: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 8	LEU P 132 ILE P 24 LEU P 23 LEU P 128	None	0.73A	2xfhA-1vtmP: undetectable	2xfhA-1vtmP: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_G_TOPG200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	5 / 12	LEU P 23 LEU P 132 ILE P 80 LEU P 79 THR P 28	None	1.04A	3fl9G-1vtmP: undetectable	3fl9G-1vtmP: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ABZ_A_T1CA1209_1 (TETRACYCLINE REPRESSOR CLASS D)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	5 / 12	PHE P 35 GLN P 45 THR P 43 GLN P 47 LEU P 23	None	1.49A	4abzA-1vtmP: undetectable	4abzA-1vtmP: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_B_MTLB806_0 (NITRIC OXIDE SYNTHASE, BRAIN)	1vtm	COAT PROTEIN (Tobacco mild green mosaic virus)	4 / 7	SER P 86 GLN P 38 ASN P 85 ASP P 88	None	1.42A	4kcnB-1vtmP: undetectable	4kcnB-1vtmP: 17.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_1","SERINE HYDROXYMETHYLTRANSFERASE","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"TYR P  68;TYR P  70;PHE P  62;PRO P  63","None","1.33A","1dfoB-1vtmP:undetectable","1dfoB-1vtmP:15.79"],["1DFO_B_FFOB2002_0","SERINE HYDROXYMETHYLTRANSFERASE","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"TYR P  68;TYR P  70;PHE P  62;PRO P  63","None","1.33A","1dfoA-1vtmP:undetectable","1dfoA-1vtmP:15.79"],["1DFO_C_FFOC3002_2","SERINE HYDROXYMETHYLTRANSFERASE","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"TYR P  68;TYR P  70;PHE P  62;PRO P  63","None","1.33A","1dfoD-1vtmP:undetectable","1dfoD-1vtmP:15.79"],["1DFO_D_FFOD4002_0","SERINE HYDROXYMETHYLTRANSFERASE","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"TYR P  68;TYR P  70;PHE P  62;PRO P  63","None","1.34A","1dfoC-1vtmP:undetectable","1dfoC-1vtmP:15.79"],["2VMY_A_FFOA505_0","SERINE HYDROXYMETHYLTRANSFERASE","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"TYR P  68;TYR P  70;PHE P  62;PRO P  63","None","1.41A","2vmyA-1vtmP:undetectable","2vmyA-1vtmP:16.50"],["2XFH_A_CL6A1414_1","ERYTHROMYCIN B\/D C-12 HYDROXYLASE","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"LEU P 132;ILE P  24;LEU P  23;LEU P 128","None","0.73A","2xfhA-1vtmP:undetectable","2xfhA-1vtmP:19.34"],["3FL9_G_TOPG200_1","DIHYDROFOLATE REDUCTASE (DHFR)","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",5,"LEU P  23;LEU P 132;ILE P  80;LEU P  79;THR P  28","None","1.04A","3fl9G-1vtmP:undetectable","3fl9G-1vtmP:18.64"],["4ABZ_A_T1CA1209_1","TETRACYCLINE REPRESSOR CLASS D","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",5,"PHE P  35;GLN P  45;THR P  43;GLN P  47;LEU P  23","None","1.49A","4abzA-1vtmP:undetectable","4abzA-1vtmP:21.15"],["4KCN_B_MTLB806_0","NITRIC OXIDE SYNTHASE, BRAIN","1vtm","COAT PROTEIN","Tobacco mild green mosaic virus",4,"SER P  86;GLN P  38;ASN P  85;ASP P  88","None","1.42A","4kcnB-1vtmP:undetectable","4kcnB-1vtmP:17.58"]]