SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vya'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vya NUCLEOSIDE
DIPHOSPHATE KINASE
(Zea
mays) 		5 / 10 LEU A  35
PHE A 131
LEU A 135
ALA A 136
PHE A  30
 None
 1.24A 1g5yC-1vyaA:
undetectable		 1g5yC-1vyaA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1vya NUCLEOSIDE
DIPHOSPHATE KINASE
(Zea
mays) 		4 / 8 ILE A 127
GLY A 134
SER A   3
GLU A  76
 None
 0.90A 1mrjA-1vyaA:
undetectable		 1mrjA-1vyaA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 1vya NUCLEOSIDE
DIPHOSPHATE KINASE
(Zea
mays) 		4 / 6 HIS A 115
GLU A 126
ASP A 118
SER A 122
 None
 1.29A 4apjA-1vyaA:
undetectable
4apjP-1vyaA:
undetectable		 4apjA-1vyaA:
14.38
4apjP-1vyaA:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 1vya NUCLEOSIDE
DIPHOSPHATE KINASE
(Zea
mays) 		3 / 3 TRP A 130
ILE A  65
GLU A  41
 None
 0.63A 6hcxA-1vyaA:
undetectable		 6hcxA-1vyaA:
17.45