SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vyh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.33A 1c9sB-1vyhA:
undetectable
1c9sC-1vyhA:
undetectable		 1c9sB-1vyhA:
17.39
1c9sC-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.37A 1gtfC-1vyhA:
undetectable
1gtfD-1vyhA:
undetectable		 1gtfC-1vyhA:
17.39
1gtfD-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 9 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.35A 1gtfF-1vyhA:
undetectable
1gtfG-1vyhA:
undetectable		 1gtfF-1vyhA:
17.39
1gtfG-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.34A 1gtfG-1vyhA:
undetectable
1gtfH-1vyhA:
undetectable		 1gtfG-1vyhA:
17.39
1gtfH-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.35A 1gtfH-1vyhA:
undetectable
1gtfI-1vyhA:
undetectable		 1gtfH-1vyhA:
17.39
1gtfI-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		3 / 3 ARG C 316
VAL C 237
TRP C 236
 None
 1.14A 1qw6A-1vyhC:
undetectable		 1qw6A-1vyhC:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		3 / 3 ARG C 316
VAL C 237
TRP C 236
 None
 1.20A 1qwcA-1vyhC:
undetectable		 1qwcA-1vyhC:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		4 / 4 SER C 288
SER C 291
LEU C 312
PHE C 310
 None
 1.36A 1r5lA-1vyhC:
0.0		 1r5lA-1vyhC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		3 / 3 GLU A 112
GLU A 119
LEU A 139
 None
 0.76A 1v8bB-1vyhA:
2.5		 1v8bB-1vyhA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		3 / 3 GLU A 113
GLU A 119
LEU A  82
 None
 0.78A 1v8bB-1vyhA:
2.5		 1v8bB-1vyhA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		3 / 3 ARG C 316
VAL C 237
TRP C 236
 None
 1.16A 1vagA-1vyhC:
undetectable		 1vagA-1vyhC:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		4 / 8 ARG C 241
ALA C 210
HIS C 191
MET C 188
 None
 1.12A 1x8vA-1vyhC:
undetectable		 1x8vA-1vyhC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 12 HIS A  28
ILE A  73
GLY A  72
LEU A  69
ILE A  93
 None
 1.27A 1zq9A-1vyhA:
undetectable		 1zq9A-1vyhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		5 / 12 HIS C 337
GLY C 343
LEU C 386
ASP C 401
VAL C 400
 None
 1.23A 1zq9A-1vyhC:
undetectable		 1zq9A-1vyhC:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VFT_A_SORA1419_0
(XYLITOL OXIDASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Homo
sapiens;
Mus
musculus) 		5 / 12 HIS C 381
VAL C 400
HIS A  67
THR C 384
ARG C 316
 None
 1.46A 2vftA-1vyhC:
0.0		 2vftA-1vyhC:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens;
Mus
musculus) 		3 / 3 ARG A  60
GLU C 100
SER A  64
 None
 0.89A 2xkkA-1vyhA:
3.2
2xkkC-1vyhA:
3.4		 2xkkA-1vyhA:
15.52
2xkkC-1vyhA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		5 / 11 SER C 109
PRO C 110
SER C 127
THR C 112
LYS C 133
 None
 1.20A 3bjwB-1vyhC:
undetectable		 3bjwB-1vyhC:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		5 / 11 SER C 109
PRO C 110
SER C 127
THR C 112
LYS C 133
 None
 1.21A 3bjwH-1vyhC:
undetectable		 3bjwH-1vyhC:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		5 / 12 HIS C 275
ILE C 353
VAL C 344
LEU C 334
THR C 333
 None
 0.95A 3fw3A-1vyhC:
0.0		 3fw3A-1vyhC:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		5 / 12 HIS C 275
ILE C 353
VAL C 344
LEU C 334
THR C 333
 None
 0.96A 3fw3B-1vyhC:
undetectable		 3fw3B-1vyhC:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 PRO A 141
THR A 175
VAL A 180
GLY A 177
GLY A 178
 None
 1.31A 3ixlA-1vyhA:
4.5		 3ixlA-1vyhA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 11 VAL A  50
PHE A 192
GLY A 201
GLY A 200
ILE A  58
 None
 1.48A 3owxA-1vyhA:
3.7
3owxB-1vyhA:
3.8		 3owxA-1vyhA:
23.97
3owxB-1vyhA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		4 / 6 ALA A 120
ALA A   9
LEU A  82
THR A  78
 None
 1.07A 4dtzB-1vyhA:
undetectable		 4dtzB-1vyhA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		4 / 7 ALA A 120
ALA A 115
ALA A   9
THR A  78
 None
 0.81A 4du2B-1vyhA:
undetectable		 4du2B-1vyhA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 12 GLY A 103
ASN A 105
HIS A 107
ILE A 121
ASN A 109
 None
 1.40A 4pooB-1vyhA:
3.4		 4pooB-1vyhA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		5 / 12 ALA C 166
VAL C 221
ILE C 207
PRO C 118
ILE C 115
 None
 1.03A 4q5mA-1vyhC:
undetectable		 4q5mA-1vyhC:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Homo
sapiens;
Mus
musculus) 		3 / 3 ASP A  41
ARG C 212
ARG C 238
 None
 0.73A 4x5iA-1vyhA:
0.1		 4x5iA-1vyhA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 11 VAL A  50
PHE A 192
GLY A 201
GLY A 200
ILE A  58
 None
 1.49A 4zvmA-1vyhA:
4.4
4zvmB-1vyhA:
2.5		 4zvmA-1vyhA:
23.60
4zvmB-1vyhA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Homo
sapiens;
Mus
musculus) 		3 / 3 ASP A  41
ARG C 212
ARG C 238
 None
 0.58A 5eajB-1vyhA:
1.1		 5eajB-1vyhA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.33A 5eeuD-1vyhA:
undetectable
5eeuE-1vyhA:
undetectable		 5eeuD-1vyhA:
17.39
5eeuE-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.35A 5eeuJ-1vyhA:
undetectable
5eeuK-1vyhA:
undetectable		 5eeuJ-1vyhA:
17.39
5eeuK-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5eevD-1vyhA:
undetectable
5eevE-1vyhA:
undetectable		 5eevD-1vyhA:
17.39
5eevE-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.34A 5eevJ-1vyhA:
undetectable
5eevK-1vyhA:
undetectable		 5eevJ-1vyhA:
17.39
5eevK-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5eewD-1vyhA:
undetectable
5eewE-1vyhA:
undetectable		 5eewD-1vyhA:
17.39
5eewE-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.35A 5eewJ-1vyhA:
undetectable
5eewK-1vyhA:
undetectable		 5eewJ-1vyhA:
17.39
5eewK-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5eexD-1vyhA:
undetectable
5eexE-1vyhA:
undetectable		 5eexD-1vyhA:
17.39
5eexE-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.35A 5eexJ-1vyhA:
undetectable
5eexK-1vyhA:
undetectable		 5eexJ-1vyhA:
17.39
5eexK-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5eeyD-1vyhA:
undetectable
5eeyE-1vyhA:
undetectable		 5eeyD-1vyhA:
17.39
5eeyE-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.35A 5eeyJ-1vyhA:
undetectable
5eeyK-1vyhA:
undetectable		 5eeyJ-1vyhA:
17.39
5eeyK-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5eezD-1vyhA:
undetectable
5eezE-1vyhA:
undetectable		 5eezD-1vyhA:
17.39
5eezE-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5ef0D-1vyhA:
undetectable
5ef0E-1vyhA:
undetectable		 5ef0D-1vyhA:
17.39
5ef0E-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5ef1D-1vyhA:
undetectable
5ef1E-1vyhA:
undetectable		 5ef1D-1vyhA:
17.39
5ef1E-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5ef2D-1vyhA:
undetectable
5ef2E-1vyhA:
undetectable		 5ef2D-1vyhA:
17.39
5ef2E-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ARG A  84
GLY A 117
HIS A  80
THR A  78
ILE A 118
 None
 1.32A 5ef3D-1vyhA:
undetectable
5ef3E-1vyhA:
undetectable		 5ef3D-1vyhA:
17.39
5ef3E-1vyhA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		3 / 3 SER C 291
SER C 294
PHE C 346
 None
 0.75A 5mugA-1vyhC:
undetectable		 5mugA-1vyhC:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ILE A 135
ILE A 213
LEU A 217
ILE A 125
ASN A 126
 None
 1.13A 5vkqA-1vyhA:
undetectable
5vkqD-1vyhA:
undetectable		 5vkqA-1vyhA:
8.60
5vkqD-1vyhA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ILE A 125
ASN A 126
ILE A 135
ILE A 213
LEU A 217
 None
 1.12A 5vkqA-1vyhA:
0.0
5vkqB-1vyhA:
0.0		 5vkqA-1vyhA:
8.60
5vkqB-1vyhA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
BETA SUBUNIT
(Homo
sapiens) 		5 / 10 ILE A 125
ASN A 126
ILE A 135
ILE A 213
LEU A 217
 None
 1.13A 5vkqC-1vyhA:
undetectable
5vkqD-1vyhA:
undetectable		 5vkqC-1vyhA:
8.60
5vkqD-1vyhA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT
(Mus
musculus) 		4 / 6 LYS C 163
PHE C 158
VAL C 119
PRO C 118
 None
 1.48A 6fgdA-1vyhC:
undetectable		 6fgdA-1vyhC:
21.65