SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLU A 388
LEU A 394
LEU A 378
GLU A 380
GLU A 384
 None
 1.38A 1a29A-1vyvA:
undetectable		 1a29A-1vyvA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		3 / 3 ARG A 160
THR A  98
VAL A 100
 None
 0.88A 1hxbA-1vyvA:
undetectable		 1hxbA-1vyvA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_2
(ANDROGEN RECEPTOR)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		4 / 4 ASN A 381
MET A 237
LEU A 378
HIS A 332
 None
 1.15A 4oktA-1vyvA:
0.0		 4oktA-1vyvA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		5 / 12 PRO A 318
LEU A 321
GLY A 225
LEU A 378
ASN A 316
 None
 1.41A 5emlA-1vyvA:
undetectable		 5emlA-1vyvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		5 / 12 LEU A 305
LEU A 307
ALA A  95
VAL A 141
ALA A 400
 None
 1.09A 5jw1B-1vyvA:
undetectable		 5jw1B-1vyvA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		4 / 7 VAL A 222
ILE A 315
VAL A 258
ALA A 312
 None
 0.71A 5ospA-1vyvA:
undetectable		 5ospA-1vyvA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1vyv CALCIUM CHANNEL
BETA-4SUBUNIT
(Rattus
norvegicus) 		4 / 7 VAL A 222
ILE A 315
VAL A 258
ALA A 312
 None
 0.73A 5osrA-1vyvA:
undetectable		 5osrA-1vyvA:
24.01