SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 1vzm OSTEOCALCIN
(Argyrosomus
regius) 		4 / 5 ALA A  38
TYR A  40
ALA A  34
TYR A  36
 None
 1.06A 1xl6A-1vzmA:
undetectable
1xl6B-1vzmA:
undetectable		 1xl6A-1vzmA:
9.22
1xl6B-1vzmA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 1vzm OSTEOCALCIN
(Argyrosomus
regius) 		4 / 4 ALA A  38
TYR A  40
ALA A  34
TYR A  36
 None
 1.10A 2wlkA-1vzmA:
undetectable
2wlkB-1vzmA:
undetectable		 2wlkA-1vzmA:
9.22
2wlkB-1vzmA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 1vzm OSTEOCALCIN
(Argyrosomus
regius) 		4 / 6 ASP A  24
ASN A  20
ALA A  22
ASP A  28
 None
 1.20A 4mdbA-1vzmA:
undetectable		 4mdbA-1vzmA:
10.62