SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 8 PHE A  73
HIS A  52
HIS A 139
LEU A 142
 None
 1.06A 1azmA-1vzvA:
undetectable		 1azmA-1vzvA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 11 LEU A  13
LEU A 116
VAL A 112
LEU A  82
HIS A  52
 None
 1.35A 1kt7A-1vzvA:
undetectable		 1kt7A-1vzvA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 11 LEU A  13
LEU A 116
VAL A 112
LEU A  82
HIS A 139
 None
 1.31A 1kt7A-1vzvA:
undetectable		 1kt7A-1vzvA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		3 / 3 THR A 158
GLU A 106
ASP A  99
 None
 0.70A 1nt2A-1vzvA:
undetectable		 1nt2A-1vzvA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 6 ARG A 148
ALA A  20
ILE A  64
PRO A  71
 None
 1.18A 1oniB-1vzvA:
undetectable
1oniC-1vzvA:
undetectable		 1oniB-1vzvA:
23.38
1oniC-1vzvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 7 ILE A  64
PRO A  71
ARG A 148
ALA A  20
 None
 1.16A 1oniD-1vzvA:
undetectable
1oniE-1vzvA:
undetectable		 1oniD-1vzvA:
23.38
1oniE-1vzvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 6 ARG A 148
ALA A  20
ILE A  64
PRO A  71
 None
 1.03A 1oniH-1vzvA:
undetectable
1oniI-1vzvA:
undetectable		 1oniH-1vzvA:
23.38
1oniI-1vzvA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 7 ILE A 228
TYR A  18
PHE A  72
ASP A  67
 None
 1.09A 2qebA-1vzvA:
undetectable		 2qebA-1vzvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 7 ILE A 228
TYR A  18
PHE A  72
ASP A  67
 None
 1.05A 2qebB-1vzvA:
undetectable		 2qebB-1vzvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 SER A 120
VAL A 119
ILE A  48
ASN A  49
PHE A  73
 None
 1.41A 2vdyA-1vzvA:
undetectable		 2vdyA-1vzvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 SER A 120
VAL A 119
ILE A  48
ASN A  49
PHE A  73
 None
 1.38A 2vdyB-1vzvA:
undetectable		 2vdyB-1vzvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 10 ALA A  16
LEU A  19
VAL A 119
ILE A  46
ILE A  48
 None
 1.09A 3jw3A-1vzvA:
undetectable		 3jw3A-1vzvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		3 / 3 ASN A 154
ASP A 156
ARG A  98
 None
 0.77A 3k13A-1vzvA:
undetectable		 3k13A-1vzvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		3 / 3 HIS A  83
PHE A  94
PHE A  95
 None
 0.80A 3lk0D-1vzvA:
0.0		 3lk0D-1vzvA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 SER A 120
VAL A 119
ILE A  48
ASN A  49
PHE A  73
 None
 1.25A 4c49A-1vzvA:
undetectable		 4c49A-1vzvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 SER A 120
VAL A 119
ILE A  48
ASN A  49
PHE A  73
 None
 1.34A 4c49B-1vzvA:
undetectable		 4c49B-1vzvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 SER A 120
VAL A 119
ILE A  48
ASN A  49
PHE A  73
 None
 1.44A 4c49D-1vzvA:
undetectable		 4c49D-1vzvA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 5 ILE A  46
PRO A  47
TYR A 155
VAL A  15
 None
 1.34A 4s0vA-1vzvA:
undetectable		 4s0vA-1vzvA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		3 / 3 PRO A 104
ARG A 107
GLU A 106
 None
 0.92A 5j6hA-1vzvA:
undetectable		 5j6hA-1vzvA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 ILE A  48
LEU A 142
VAL A  61
GLY A  75
TYR A 155
 None
 0.96A 5nnaB-1vzvA:
undetectable		 5nnaB-1vzvA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		5 / 12 ILE A  48
LEU A 142
VAL A  61
GLY A  75
TYR A 155
 None
 0.91A 5nnaC-1vzvA:
undetectable		 5nnaC-1vzvA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 1vzv VARICELLA-ZOSTER
VIRUS PROTEASE
(Human
alphaherpesvirus
3) 		4 / 7 VAL A  77
PRO A  71
PHE A  72
LEU A  19
 None
 0.97A 6aycA-1vzvA:
undetectable		 6aycA-1vzvA:
17.07