SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vzy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 8 TYR A  10
SER A 156
ILE A 177
LEU A 195
 None
 0.89A 1eupA-1vzyA:
undetectable		 1eupA-1vzyA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 11 PRO A 211
VAL A 231
TYR A   3
GLY A  83
TYR A  17
 None
 1.37A 1fkpA-1vzyA:
undetectable		 1fkpA-1vzyA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		3 / 3 CYH A 237
ARG A 241
CYH A 235
 ZN  A1291 (-2.2A)
None
ZN  A1291 (-2.2A)
 1.17A 1p9gA-1vzyA:
undetectable		 1p9gA-1vzyA:
5.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 4 LEU A  52
SER A 150
LEU A  56
LEU A  62
 None
 0.97A 1yajA-1vzyA:
undetectable		 1yajA-1vzyA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 5 LEU A 139
VAL A  14
LEU A 179
ARG A 194
 None
 1.11A 2oiqA-1vzyA:
undetectable		 2oiqA-1vzyA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 THR A  21
ILE A 214
GLY A 160
ALA A  18
ALA A  40
 None
 1.18A 2yvlD-1vzyA:
undetectable		 2yvlD-1vzyA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 VAL A 157
ILE A 176
PHE A 128
GLU A 151
GLN A 178
 None
 1.35A 3apwB-1vzyA:
undetectable		 3apwB-1vzyA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		3 / 3 GLU A 199
LEU A 204
LEU A 170
 None
 0.66A 3ohtA-1vzyA:
undetectable		 3ohtA-1vzyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		3 / 3 GLU A 199
LEU A 204
LEU A 170
 None
 0.66A 3ohtB-1vzyA:
undetectable		 3ohtB-1vzyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 ARG A  30
GLN A  29
GLY A  33
SER A  90
GLU A  27
 None
 1.25A 3sxjA-1vzyA:
undetectable		 3sxjA-1vzyA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 ARG A  30
GLN A  29
GLY A  33
SER A  90
GLU A  27
 None
 1.25A 3sxjB-1vzyA:
undetectable		 3sxjB-1vzyA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 ARG A  30
GLN A  29
GLY A  33
SER A  90
GLU A  27
 None
 1.24A 3t7sB-1vzyA:
undetectable		 3t7sB-1vzyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 ARG A  30
GLN A  29
GLY A  33
SER A  90
GLU A  27
 None
 1.26A 3t7sD-1vzyA:
undetectable		 3t7sD-1vzyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 6 THR A 112
GLY A  68
ARG A  44
ILE A  66
 None
 1.04A 4ac9C-1vzyA:
undetectable		 4ac9C-1vzyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 6 THR A 112
GLY A  68
ARG A  44
ILE A  66
 None
 1.05A 4acaC-1vzyA:
undetectable		 4acaC-1vzyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 6 THR A 112
GLY A  68
ARG A  44
ILE A  66
 None
 1.02A 4acbC-1vzyA:
undetectable		 4acbC-1vzyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 7 ASN A  99
VAL A 106
GLU A 138
ARG A  44
 None
 0.93A 4mv7A-1vzyA:
undetectable		 4mv7A-1vzyA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		3 / 3 ASP A  78
ARG A 241
PRO A 236
 None
 1.03A 4wanC-1vzyA:
0.0		 4wanC-1vzyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 12 LEU A 104
ALA A  40
LEU A  42
LEU A 162
GLY A 174
 None
 1.03A 4xi3C-1vzyA:
undetectable		 4xi3C-1vzyA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		3 / 3 VAL A 218
SER A 156
MET A 180
 None
 0.89A 5ikqA-1vzyA:
0.0		 5ikqA-1vzyA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 8 VAL A  85
ALA A  48
THR A  47
VAL A  25
HIS A  32
 None
 1.27A 5l94A-1vzyA:
undetectable		 5l94A-1vzyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 4 GLU A 213
PRO A 211
ILE A 214
LEU A 209
 None
 1.17A 5m45A-1vzyA:
1.4		 5m45A-1vzyA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		4 / 4 GLU A 213
PRO A 211
ILE A 214
LEU A 209
 None
 1.23A 5m45J-1vzyA:
undetectable		 5m45J-1vzyA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 1vzy 33 KDA CHAPERONIN
(Bacillus
subtilis) 		5 / 11 LEU A  42
MET A  46
THR A  47
THR A  22
ASN A  26
 None
 1.49A 6hupA-1vzyA:
0.1
6hupB-1vzyA:
0.0		 6hupA-1vzyA:
14.78
6hupB-1vzyA:
13.50